Results 31 to 40 of about 1,235,212 (309)
PLoS ONEThe National Sustainable Development Agenda Innovation Demonstration Zones (NSDAIDZs) aim to spearhead green development through scientific and technological innovation, showcasing sustainable development to other regions in China and offering valuable ...
Qingqing Yuan +4 more
doaj +1 more source
Achieving Effective Innovation Based On TRIZ Technological Evolution [PDF]
, 2009 Organised by: Cranfield UniversityThis paper outlines the conception of effective innovation and discusses the method to achieve it. Effective Innovation is constrained on the path of technological evolution so that the corresponding path must be ...
Cao, G. Z., Sun, J. G., Tan, R. H.
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Energy Reports, 2022 Under the constraint of “double carbon” goal, both environmental regulation and resource endowment are important factors affecting the technological innovation efficiency. Based on the panel data of Chinese renewable energy enterprises from 2010 to 2019,
Tao Shen +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
EVALUATION OF TECHNOLOGY INNOVATION IN HUBEI PROVINCE [PDF]
Engineering Heritage Journal, 2018 Innovation is the soul of a nation's progress and the inexhaustible motive force of a country's prosperity. This paper analyzes the status of technological innovation in Hubei province by constructing the evaluation index system of technological ...
Song Tao
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Revista INGI, 2019 Múltiplos fatores influenciam o baixo número de tecnologias consideradas de sucesso protegidas no Brasil, em especial a cultura que persiste nas academias brasileiras, que insiste em não proteção e obtenção de benefícios intelectuais, financeiros e ...
Rodrigo Pereira Barata +1 more
doaj
Acta Scientiarum: TechnologyThe current study was undertaken to evaluate the performance of Lactobacillus plantarum CT28 strain as probiotic culture compared to thecommercial starter cultureon the quality of fermented goat sausage samples during 28 days of ripening period ...
Ameni Telmoudi +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source