Results 41 to 50 of about 303,086 (310)

SCIENTIFIC AND TECHNOLOGICAL INNOVATION [PDF]

open access: yesAnnals: Series on engineering sciences (Academy of Romanian Scientists), 2011
Today, science and, accordingly, scientific research is widely recognized as the main driving force of production and source of innovation and technology transfer.
Gabriel I. NASTASE   +2 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Technological innovation persistence : Literature survey and exploration of the role of organizational innovation [PDF]

open access: yes
In this paper, we will review the literature on technological innovation persistence and provide a general theoretical framework to analyze the main determinants of this innovative behavior.
Christian Le Bas   +2 more
core   +2 more sources

Workplace Innovation and Technological Change. CEPS Special Report, September 2012 [PDF]

open access: yes, 2012
This paper explores the extent to which the illusive phenomenon of workplace innovation has pervaded workplaces in Europe and whether it could be one of the answers to Europe’s longterm social and economic challenges that stem from an ageing workforce ...
Beblavý, Miroslav   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Financial strategy for modernization of fixed capital of Russian enterprises to strengthen their technological sovereignty

open access: yesRUDN Journal of Economics
The study focuses on the problem of maintaining Russia’s forward position in the Fourth Industrial Revolution. The study is devoted to the development of scientific and practical recommendations for improving the financial support for the modernization ...
Tatiana N. Litvinova   +3 more
doaj   +1 more source

Empirical study of national technological innovation capability in Africa

open access: yesSouth African Journal of Economic and Management Sciences, 2012
This paper performs an analysis of the technological innovation capability in 30 African countries. Based on the literature about national innovation capability and economy of technological change, an empirical study using clusters’ analysis technique ...
Mónica García-Ochoa Mayor   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

EVALUATION OF TECHNOLOGY INNOVATION IN HUBEI PROVINCE [PDF]

open access: yesEngineering Heritage Journal, 2018
Innovation is the soul of a nation's progress and the inexhaustible motive force of a country's prosperity. This paper analyzes the status of technological innovation in Hubei province by constructing the evaluation index system of technological ...
Song Tao
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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