Results 31 to 40 of about 303,086 (310)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
PLoS ONEThe National Sustainable Development Agenda Innovation Demonstration Zones (NSDAIDZs) aim to spearhead green development through scientific and technological innovation, showcasing sustainable development to other regions in China and offering valuable ...
Qingqing Yuan +4 more
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Energy Reports, 2022 Under the constraint of “double carbon” goal, both environmental regulation and resource endowment are important factors affecting the technological innovation efficiency. Based on the panel data of Chinese renewable energy enterprises from 2010 to 2019,
Tao Shen +3 more
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Information Technology Innovation [PDF]
The Permanente Journal, 2008 “Innovation is what distinguishes between a leader and a follower” is a statement often attributed to Apple cofounder Steve Jobs. Nowhere is this saying truer than in the realm of information technology (IT), where the blistering pace of change can make even casual observers dizzy. Yet IT innovation can be a two-edged sword.
openaire +2 more sources
Technological Innovation Revisited [PDF]
Molecular & Cellular Proteomics, 2010 As the journal moves into its 10th year of publication, it (really those charged with its editorial well-being) continues to monitor developments in the field of proteomics, including activities in the related fields of genomics, transcriptomics, and metabolomics, with the view of introducing appropriate changes to accommodate them.
Ralph A, Bradshaw, A L, Burlingame
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Revista INGI, 2019 Múltiplos fatores influenciam o baixo número de tecnologias consideradas de sucesso protegidas no Brasil, em especial a cultura que persiste nas academias brasileiras, que insiste em não proteção e obtenção de benefícios intelectuais, financeiros e ...
Rodrigo Pereira Barata +1 more
doaj
Technological innovation and profit
Journal of Open Innovation: Technology, Market and ComplexityThis study examines the effect of technological innovation on economic performance. Solow’s growth accounting measures the contribution of productivity to economic growth, but the active role of technological change in attaining economic growth is ...
Sanghoon Lee
doaj +1 more source