Results 31 to 40 of about 3,507,289 (303)

Branching innovation, recombinant innovation, and endogenous technological transitions [PDF]

, 2012
We propose a model of technological transitions based on two different types of innovations. Branching innovations refer to technological improvements along a particular path, while recombinant innovations represent fusions of multiple paths. Recombinant
Izquierdo, L.R., Zeppini, Paolo, Frenken, K., Frenken, Koen, Zeppini, P Paolo, Frenken, K Koen, Izquierdo, LR, Innovation Studies, Izquierdo, Luis, Dynamics of Innovation Systems, Izquierdo, L., Zeppini, P.   +11 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Does technological innovation in National Sustainable Development Agenda Innovation Demonstration Zones promote green development?-the case from Chengde City, China.

PLoS ONE
The National Sustainable Development Agenda Innovation Demonstration Zones (NSDAIDZs) aim to spearhead green development through scientific and technological innovation, showcasing sustainable development to other regions in China and offering valuable ...
Qingqing Yuan, Guofeng Zhang, Ruixian Wang, Xiaojing Ma, Jiangao Niu   +4 more
doaj   +1 more source

SCIENTIFIC AND TECHNOLOGICAL INNOVATION [PDF]

Annals: Series on engineering sciences (Academy of Romanian Scientists), 2011
Today, science and, accordingly, scientific research is widely recognized as the main driving force of production and source of innovation and technology transfer.
Gabriel I. NASTASE, Dragos Ionut G. NASTASE, Cristina ILIESCU   +2 more
doaj  

Does Technological Innovation Promote Haze Pollution Control? New Evidence Based on Panel Threshold Model and Spatial Econometric Model

Frontiers in Environmental Science, 2022
Since the reform and opening up, China’s rapid economic growth mainly depends on the industrial development mode of “high energy consumption and high pollution,” which has caused serious haze pollution.
Weiwei Shi, Lin Zhang
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Financial strategy for modernization of fixed capital of Russian enterprises to strengthen their technological sovereignty

RUDN Journal of Economics
The study focuses on the problem of maintaining Russia’s forward position in the Fourth Industrial Revolution. The study is devoted to the development of scientific and practical recommendations for improving the financial support for the modernization ...
Tatiana N. Litvinova, Olga V. Konina, Yuliya A. Kopytina, Elena S. Akopova   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

APIT (AFFERING TECHNOLOGICAL INNOVATION POTENTIAL): METHODOLOGY FOR AFFECTING TECHNOLOGICAL INNOVATION POTENTIAL

Revista INGI, 2019
Múltiplos fatores influenciam o baixo número de tecnologias consideradas de sucesso protegidas no Brasil, em especial a cultura que persiste nas academias brasileiras, que insiste em não proteção e obtenção de benefícios intelectuais, financeiros e ...
Rodrigo Pereira Barata, Tecia Vieira Carvalho   +1 more
doaj