Results 41 to 50 of about 1,224,454 (289)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

SCIENTIFIC AND TECHNOLOGICAL INNOVATION [PDF]

Annals: Series on engineering sciences (Academy of Romanian Scientists), 2011
Today, science and, accordingly, scientific research is widely recognized as the main driving force of production and source of innovation and technology transfer.
Gabriel I. NASTASE, Dragos Ionut G. NASTASE, Cristina ILIESCU   +2 more
doaj  

Empirical study of national technological innovation capability in Africa

South African Journal of Economic and Management Sciences, 2012
This paper performs an analysis of the technological innovation capability in 30 African countries. Based on the literature about national innovation capability and economy of technological change, an empirical study using clusters’ analysis technique ...
Mónica García-Ochoa Mayor, María Luisa Blázquez de la Hera, Enrique de Diego Ruiz   +2 more
doaj   +1 more source

Impact of scientific and technological innovation policies on innovation efficiency of high-technology industrial parks – A dual analysis with linear regression and QCA

International Journal of Innovation Studies, 2022
Scientific and technological innovation policies play a critical role in the innovative development of high-technology industrial parks. However, it remains unclear how scientific and technological innovation policies impact the innovation efficiency of ...
Jinglei Wang, Xiao Ma, Yixuan Zhao, Jing Zhao, Mohammad Heydari   +4 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Development of novel fermented goat sausage inoculated with Lactobacillus plantarum probiotic bacteria

Acta Scientiarum: Technology
The current study was undertaken to evaluate the performance of Lactobacillus plantarum CT28 strain as probiotic culture compared to thecommercial starter cultureon the quality of fermented goat sausage samples during 28 days of ripening period ...
Ameni Telmoudi, Imen Mahmoudi, Moncef Chouaibi, Mnasser Hassouna   +3 more
doaj   +1 more source

Technological Innovation

Journal of Global Information Management, 2018
The Mobile Internet Information Technology (MIIT) has been widely accepted as one of the most promising technologies in the next decades, having various applications and different value positions. However, few published studies explore and examine the effects of MIIT on community management.
Su, Wan, Xu, Xiaobo, Li, Yangchun, Martinez-Lopez, Francisco J., Li, Ling   +4 more
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Influencing Factors Analysis in Railway Engineering Technological Innovation under Complex and Difficult Areas: A System Dynamics Approach

Mathematics
The geological complexity, environmental sensitivity, and ecological fragility inherent in complex and difficult areas (CDAs) present new opportunities and challenges for technological innovation in railway engineering development in China.
Chaoxun Cai, Shiyu Tian, Yuefeng Shi, Yongjun Chen, Xiaojian Li   +4 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source