Results 41 to 50 of about 1,235,212 (309)

Open Innovation, ambiguity and technological convergence [PDF]

, 2017
Objectives. Current paper aims to provide a fresh conceptual framework on the relationship among open innovation, decision ambiguity, and technological convergence.
Ferri, M. A., Orlando, B., Renzi, A., Sancetta, G.   +3 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

SCIENTIFIC AND TECHNOLOGICAL INNOVATION [PDF]

Annals: Series on engineering sciences (Academy of Romanian Scientists), 2011
Today, science and, accordingly, scientific research is widely recognized as the main driving force of production and source of innovation and technology transfer.
Gabriel I. NASTASE, Dragos Ionut G. NASTASE, Cristina ILIESCU   +2 more
doaj  

Empirical study of national technological innovation capability in Africa

South African Journal of Economic and Management Sciences, 2012
This paper performs an analysis of the technological innovation capability in 30 African countries. Based on the literature about national innovation capability and economy of technological change, an empirical study using clusters’ analysis technique ...
Mónica García-Ochoa Mayor, María Luisa Blázquez de la Hera, Enrique de Diego Ruiz   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Technological Innovation

Journal of Global Information Management, 2018
The Mobile Internet Information Technology (MIIT) has been widely accepted as one of the most promising technologies in the next decades, having various applications and different value positions. However, few published studies explore and examine the effects of MIIT on community management.
Su, Wan, Xu, Xiaobo, Li, Yangchun, Martinez-Lopez, Francisco J., Li, Ling   +4 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Technological innovation and profit

Journal of Open Innovation: Technology, Market and Complexity
This study examines the effect of technological innovation on economic performance. Solow’s growth accounting measures the contribution of productivity to economic growth, but the active role of technological change in attaining economic growth is ...
Sanghoon Lee
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Influencing Factors Analysis in Railway Engineering Technological Innovation under Complex and Difficult Areas: A System Dynamics Approach

Mathematics
The geological complexity, environmental sensitivity, and ecological fragility inherent in complex and difficult areas (CDAs) present new opportunities and challenges for technological innovation in railway engineering development in China.
Chaoxun Cai, Shiyu Tian, Yuefeng Shi, Yongjun Chen, Xiaojian Li   +4 more
doaj   +1 more source