Results 101 to 110 of about 47,818 (311)
Scholarship, leadership and technology
ASCILITE Publications, 2011 This case study describes how one university is addressing the challenge of embedding evidence- based practice in learning, teaching and technology by building on the concept of distributive leadership. Following its launch in 2008, the Caledonian Scholars and Associates initiative has firmly established itself as a key aspect of continuing ...
openaire +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The technological relationships between indigenous firms and foreign-owned MNCs in the European regions [PDF]
It has been argued that the accumulation of technological competence is a path-dependent and context-specific process, being partly firm-specific and partly location-specific.
Simona Iammarino, John Cantwell
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Polarization in Higher Education and Technological Leadership [PDF]
This paper highlights the role of polarization in higher education as a key factor to technological leadership as well as to labor market inequality.
Brezis, Elise, Rubin, Amir
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
ASCILITE Publications, 2010 While research has found that technology leadership is an important factor for effective integration of technology in schools, there is a paucity of research on technology leadership in schools. This paper reviewed 12 empirical reports on technology leadership and a grounded theory approach was used to derive the key findings.
openaire +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Economic mechanisms of structural transformations and technological leadership in economy
Векторы благополучия: экономика и социумThe article examines economic mechanisms aimed at accelerating innovative sustainable development and achieving technological leadership in the national economy.
E.A. Gasanov +3 more
doaj +1 more source