Results 111 to 120 of about 245,064 (314)
Third Annual Acquisition Research Symposium Proceedings [PDF]
, 2006 Third Annual Acquisition Research SymposiumThose familiar with the Naval Postgraduate School's Acquisition Research Program know that, since its inception in 2003, we have promoted the idea of big A Acquisition as a core theme.
core
Geothermal Reservoir Technology Research Program: Abstracts of selected research projects [PDF]
, 1993 Research projects are described in the following areas: geothermal exploration, mapping reservoir properties and reservoir monitoring, and well testing, simulation, and predicting reservoir performance. The objectives, technical approach, and project status of each project are presented.
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
On Semi-Industrialized Countries and the Acquisition of Technological Capabilities. [PDF]
The last decades have witnessed a breaking down of the hitherto quasi-monopoly in industrial and technological development by highly industrialized countries.
Simon Teitel
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Climate policy and corporate artificial intelligence: Evidence from low-carbon city pilots in China
Environmental and Sustainability IndicatorsThe Low-Carbon City Pilot (LCCP) program in China is a climate policy implemented at the city level, and its impact on the development of corporate artificial intelligence (AI) remains to be studied.
Longsheng Wu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Аграрная наука Евро-Северо-ВостокаWater is used in the whole cycle of milk production, from watering and fodder preparation to washing of milking equipment and milk cooling tanks. At the same time, farms do not control and record the amount of water consumed, which can result in a ...
V. V. Gordeev +3 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source