Results 71 to 80 of about 1,592,092 (307)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Social Acceptance of Nuclear Energy Among Y and Z-Generation Hungarian Residents

Theory, Methodology, Practice
Governments all over the world are trying to find the balance between the constantly increasing electricity demand of their countries’ economy, while mitigating the negative effects of energy generation on the atmosphere (especially CO2 emission ...
Péter Bihari
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A study into user acceptance of new technology: British Airways ground transport department Heathrow Terminal 5 [PDF]

, 2009
This project was conducted with the help and encouragement of British Airways (BA) management. It was carried out at Heathrow Airport, Terminal 5 (T5) where a new Resource Management System (RMS) that is based upon Internet Protocol (IP) has been ...
McCool, Clare K.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

USER ACCEPTANCE OF MOBILE-JKN: INSIGHTS FROM THE TECHNOLOGY ACCEPTANCE MODEL

Jurnal Administrasi Kesehatan Indonesia
Background: Technological advancements in healthcare have driven BPJS Kesehatan Indonesia to develop the Mobile JKN application to enhance accessibility, efficiency, and quality of services.
Ferina Septiani Damanik, Anna Wahyuni Widayanti, Chairun Wiedyaningsih   +2 more
doaj   +1 more source

Validity of the technology acceptance model (TAM) : A sensemaking perspective [PDF]

, 2007
This study investigates whether sensemaking activities influence technology acceptance and if the strength of relationship between TAM’s constructs changes over a period of time. This study was a panel-based longitudinal study, whereby data was collected
Aafaqi, Bushra, Jantan, Muhamad, Ramayah, T.   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Predicting teachers' use of an educational system by intention, attitude and self-reported use [PDF]

, 2013
Acceptance studies are for organizations a means to gain insight into users’ perceptions of a (newly introduced) technology. However, the validity of an acceptance study might be limited (a) in the case where a technology can be used receptively (e.g. to
Pynoo, Bram, van Braak, Johan
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source