Results 111 to 120 of about 7,828,899 (356)

NASA/General Electric broad-specification fuels combustion technology program, phase 1 [PDF]

open access: yes, 1980
The use of broad specification fuels in aircraft turbine engine combustion systems was examined. Three different combustor design concepts were evaluated for their ability to use broad specification fuels while meeting several specific emissions ...
Dodds, W. J.
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Production Under Uncertainty: A Simulation Study [PDF]

open access: yes
In this article we model production technology in a state-contingent framework. Our model analyzes production under uncertainty without regard to the nature of producer risk preferences. In our model producers?
C.J. O’Donnell   +2 more
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Knowledge Management Systems as an Interdisciplinary Communication and Personalized General-Purpose Technology [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2015
As drivers of human civilization, Knowledge Management (KM) processes have co-evolved in line with General-Purpose-Technologies (GPT), such as writing, printing, and information and communication systems. As evidenced by the recent shift from information
Ulrich Schmitt
doaj  

Space Shuttle Lightning Protection [PDF]

open access: yes, 1979
The technology for lightning protection of even the most advanced spacecraft is available and can be applied through cost-effective hardware designs and design-verification techniques.
Blount, R. L.   +2 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

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