Results 111 to 120 of about 8,042,294 (313)
How cumulative is technological knowledge? [PDF]
arXiv, 2020 Technological cumulativeness is considered one of the main mechanisms for technological progress, yet its exact meaning and dynamics often remain unclear. To develop a better understanding of this mechanism we approach a technology as a body of knowledge consisting of interlinked inventions.
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Social approaches to technological systems
Trilogía Ciencia Tecnología Sociedad, 2014 this article presents a characterization of technological systems from social approaches. This is a set of elements that seek to define both the functioning and the role of people in technological systems.
Carlos Osorio Marulanda
doaj +1 more source
A feasibility study for advanced technology integration for general aviation [PDF]
An investigation was conducted to identify candidate technologies and specific developments which offer greatest promise for improving safety, fuel efficiency, performance, and utility of general aviation airplanes. Interviews were conducted with general
Hawley, K. E. +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Construction of energy internet technology architecture based on general system structure theory
Energy Reports, 2021 Based on electrical power systems, leveraging renewable energy generation technology, and information technology, the energy internet fuses power grids, gas networks, heat/cold supply networks, electric transportation networks, etc.
Jian Geng +8 more
doaj
The Generations of Sequencing Technologies: An Overview
, 2020 The world has now entered into a replacement era of genomics due to the continued advancements within the next generation high throughput sequencing technologies, which incorporates sequencing by synthesis-fluorescent in place sequencing (FISSEQ), pyrosequencing, sequencing by ligation using polony amplification, supported oligonucleotide detection ...
Adesiyan, Ayobami +5 more
openaire +3 more sources
, 2013 This paper focuses on the development of a general interaction framework to help design technology to support communication between people and improve interactions between people, technology and objects, particularly in complex situations when disabled ...
Angkananon, Kewalin +2 more
core +1 more source
Ensuring Responsible Outcomes from Technology [PDF]
arXiv, 2019 We attempt to make two arguments in this essay. First, through a case study of a mobile phone based voice-media service we have been running in rural central India for more than six years, we describe several implementation complexities we had to navigate towards realizing our intended vision of bringing social development through technology.
arxiv
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source