Results 131 to 140 of about 8,042,294 (313)

The hybrid dilemma -- do hybrid technologies play a transitionary or stationary role in transitions processes? [PDF]

arXiv
This research unravels the stationary or transitionary dilemma of hybrid technologies in transitions processes. A system dynamics technology interaction framework is built and simulated based on Technological Innovation System and Lotka-Volterra to investigate the inter-technology relationship impacts and modes that hybrid technologies establish with ...
arxiv  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Knowledge Management Systems as an Interdisciplinary Communication and Personalized General-Purpose Technology [PDF]

Journal of Systemics, Cybernetics and Informatics, 2015
As drivers of human civilization, Knowledge Management (KM) processes have co-evolved in line with General-Purpose-Technologies (GPT), such as writing, printing, and information and communication systems. As evidenced by the recent shift from information
Ulrich Schmitt
doaj  

An assessment of General Aviation utilization of advanced avionics technology [PDF]

Needs of the general aviation industry for services and facilities which might be supplied by NASA were examined. In the data collection phase, twenty-one individuals from nine manufacturing companies in general aviation were interviewed against a ...
Quinby, G. F.
core   +1 more source

Teacher change in a developing curriculum area: the example of trade teachers in the New Zealand technology curriculum [PDF]

, 2000
Technology education for all students is a relatively new phenomenon in national and international curricula. Although New Zealand has a long history of technical education in the senior primary and secondary school, a curriculum for technology education
Ewington, Louis, Jones, Alister
core   +1 more source

Pathway to the PiezoElectronic Transduction Logic Device

, 2015
The information age challenges computer technology to process an exponentially increasing computational load on a limited energy budget - a requirement that demands an exponential reduction in energy per operation.
Armstrong, C., Bryce, B. A., Copel, M., Elmegreen, B. G., Gordon, M. S., Haensch, W., Hung, L. -W., Keech, R., Kuroda, M. A., Liu, X. -H., Martyna, G. J, Miyazoe, H., Newns, D. M., Reuter, K. B., Rossnagel, S. M., Schrott, A. G., Shaw, T. M., Shett, S., Solomon, P. M., Theis, T. N., Trolier-McKinstry, S.   +20 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Determinants of technology adoption in Mexico [PDF]

The author tries to identify the impact of firm-, region-, and industry-specific characteristics on technology adoption by Mexican firms. Cross-sectional and panel data from 1992-99 show that the firms most likely to adopt new technology are large, train
Lopez-Acevedo, Gladys
core  

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

The Effective Use of Multimedia Distance Learning Technology: The Role of Technology Self-Efficacy, Attitudes, Reliability, Use and Distance in a Global Multimedia Distance Learning Classroom [PDF]

, 2000
According to the 1999 ASTD State of the Industry Report, the use of multimedia distance learning (MDL) technology for training delivery has increased substantially over the past few years.
Cavanaugh, Marcie A., Milkovich, George T., Tang, Judy   +2 more
core   +1 more source