Results 51 to 60 of about 5,547,029 (292)
Implementing technological intelligence systems from the viewpoint of complexity theory
Ingeniería e Investigación, 2008 Technology currently plays a very important role in organisations’ development and competitiveness, thus requiring suitable handling. Technology management has been strengthened by integrating new systematically-applied concepts, such as technological ...
María Elena García Vergara +2 more
doaj
The propagation of technology management taxonomies for evaluating investments in information systems [PDF]
, 2001 To provide managers with a critical insight into the management of new technology, this paper uses a case study research strategy to examine the technology management experiences of a leading UK manufacturing organization during its adoption of a vendor ...
Irani, Z, Love, PE
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Online Technology Management Student Tutorial Case Study [PDF]
, 2010 This paper presents a case study of implementing online video-based tutorials to enhance student learning. Initially, these tutorials were developed using a software product, Camtasia, to mitigate learning differences between traditional-based classrooms
Kuzma, Joanne
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Challenges to radical innovation: A car for the future: Part one [PDF]
Megatrend Revija, 2020 The car of the future is one of the most fashionable issues in the press, in political sketches and in academia. This first article is dealing with the various available options for automotive power train: gasoline, diesel, bio-fuels, natural gas ...
Chanaron Jean-Jacques
doaj
IEEE Access, 2020 Blockchain is expected to have a transformational effect on supply chain and logistics due to its promise to improve the information flow between the supply chain partners.
Niels Hackius, Moritz Petersen
doaj +1 more source
Development of Nano-economy as a Factor of Forming the Effective National Innovation System of Singapore [PDF]
, 2016 The article reveals the theoretical and methodological interpretation of the innovation system, when it determined the structure of the national innovation system. It is noted that the components of the national innovation system are elements, stages and
Ostapenko, T. (Tetiana)
core +2 more sources