Results 61 to 70 of about 1,158 (177)

Process For The Preparation of Teduglutide [PDF]

open access: yes
The present invention relates to a process for the preparation of ...
, Srinivasan Thirumalai Rajan; Ghojala Venkat Reddy; Katta Laxmi Reddy; Koduru Venkata Subba Reddy; Ayinavalli Ramesh Babu; MSN Life Sciences Private Limited, Unit-II; Hyderabad, India
core   +1 more source

Retrospective chart review of immobilized lipase cartridge use in children with short bowel syndrome

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1488-1494, June 2026.
Abstract This retrospective, single‐center chart review studied the use of an in‐line, immobilized lipase cartridge (ILC) in children with short bowel syndrome (SBS) at Children's Mercy Hospital. For parenteral nutrition (PN)‐dependent patients, the primary endpoint was enteral feeding progression, evaluated by comparing monthly change from baseline in
Elizaveta Khenner   +6 more
wiley   +1 more source

Teduglutide for the treatment of patients with short bowel syndrome

open access: yes, 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the safety and efficacy of teduglutide for the treatment of patients with short bowel syndrome when compared with placebo or no ...
Villarroel del Pino, Luis A   +10 more
core   +1 more source

Short bowel syndrome and intestinal failure in adults: Anatomy-driven phenotypes, adaptation biology, and contemporary intestinal rehabilitation [PDF]

open access: yesHalo 194
Short bowel syndrome (SBS) is the leading cause of chronic intestinal failure in adults and most commonly follows extensive small-bowel resection. The resulting loss of absorptive surface and regulatory feedback leads to a spectrum of malabsorption ...
Stojanović Bojan   +6 more
doaj   +1 more source

Pharmacokinetics and Safety of Single‐Dose Apraglutide in Individuals with Normal and Impaired Hepatic Function: A Phase 1, Open‐Label Trial

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Intestinal failure‐associated liver disease occurs in 20% to 30% of patients with short bowel syndrome and intestinal failure (SBS‐IF). Apraglutide is a glucagon‐like peptide‐2 (GLP‐2) analog in clinical development for the treatment of patients with SBS‐IF.
Gerard Greig   +4 more
wiley   +1 more source

Teduglutide, a novel glucagon-like peptide 2 analog, in the treatment of patients with short bowel syndrome

open access: yesTherapeutic Advances in Gastroenterology, 2012
Short bowel syndrome results from surgical resection, congenital defect or disease-associated loss of absorption. Parenteral support (PS) is lifesaving in patients with short bowel syndrome and intestinal failure who are unable to compensate for their ...
Palle Bekker Jeppesen
doaj   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

open access: yesSmall Methods, Volume 10, Issue 2, 22 January 2026.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz   +5 more
wiley   +1 more source

Teduglutide for intestinal failure following multivisceral transplantation complicated by graft rejection and PTLD: A case report

open access: yesIntestinal Failure
Multivisceral transplantation (MVT) is an increasingly utilized option for patients with complex abdominal pathology. However, complications such as graft rejection and post-transplant lymphoproliferative disorder (PTLD) may result in recurrent ...
Royston Antony Fernandes   +6 more
doaj   +1 more source

Short Bowel Syndrome and Kidney Transplantation: Challenges, Outcomes, and the Use of Teduglutide

open access: yesCase Reports in Transplantation, 2020
Among patients with short bowel syndrome who commonly have kidney disease, kidney transplantation remains challenging. We describe the clinicopathologic course of a 59-year old man with short bowel syndrome secondary to Crohn’s disease who underwent a ...
Elizabeth Abou Diwan   +8 more
doaj   +1 more source

An updated overview of glucagon-like peptide-2 analog trophic therapy for short bowel syndrome in adults

open access: yesJournal of International Medical Research, 2022
Short bowel syndrome (SBS) is a clinical condition characterized by a failure to achieve optimal intestinal adaptation, which is necessary to maintain oral/enteral autonomy.
Changzhen Zhu, Yuanxin Li
doaj   +1 more source

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