Results 71 to 80 of about 1,158 (177)
Long-term teduglutide for the treatment of patients with intestinal failure associated with short bowel syndrome [PDF]
, 2015 OBJECTIVES: In the pivotal 24-week, phase III, placebo-controlled trial, teduglutide significantly reduced parenteral support (PS) requirements in patients with short bowel syndrome (SBS). STEPS-2 was a 2-year, open-label extension of that study designed Fujioka, K, O'Keefe, SJ, Youssef, NN, Gabe, SM, Pape, UF, Lamprecht, G, Schwartz, LK, Jeppesen, PB, Li, B +8 morecore +1 more sourceIntestinal and Multivisceral Transplantation: Where We Stand Today
Pediatric Transplantation, Volume 30, Issue 1, January 2026.ABSTRACT
Intestinal and multivisceral transplantation has evolved from an experimental to a life‐saving procedure for children and adults with complications of gut failure (GF). Suboptimal long‐term outcomes of transplant elicit recent advances in surgical and medical gut rehabilitation along with the introduction of glucagon‐like peptide‐2 (GLP‐2 ...Mohamed Maklad, Mohammed Osman, Mariam Ismail, Tetsuya Tajima, Kadakkal Radhakrishnan, Masato Fujiki +5 morewiley +1 more sourceThe Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman +206 morewiley +1 more sourceCost-effectiveness of teduglutide in pediatric patients with short bowel syndrome: Markov modeling using traditional cost-effectiveness criteria
, 2020 BACKGROUND: Teduglutide use in pediatric patients with short bowel syndrome can aid in the achievement of enteral autonomy, but with a price of >$400,000 per y.Raghu, Vikram Kalathur, Smith, Kenneth J, Kenneth J Smith, Rudolph, Jeffrey A, Jeffrey A Rudolph, Vikram Kalathur Raghu +5 morecore +1 more sourceShort bowel syndrome–associated intestinal failure patient experience: A mixed‐method study leveraging an online patient community
Nutrition in Clinical Practice, Volume 40, Issue 5, Page 1115-1124, October 2025.Abstract Background
Patients with short bowel syndrome–associated intestinal failure (SBS‐IF) require complex, personalized, and multidisciplinary care; however, there are disparities in access. This study measured the impact of unmet needs and treatment burden among patients and their caregivers.Brian Po‐Han Chen, Josh Feldman, Megan Gower, Michelle Kirby, Brian Terreri, Maggie McCue, Manpreet S. Mundi +6 morewiley +1 more sourceFactors Associated With Response to Teduglutide in Patients With Short-Bowel Syndrome and Intestinal Failure [PDF]
, 2018 Background & Aims: Clinical studies showed teduglutide to increase urine production and reduce need for parenteral support volume in patients with short bowel syndrome (SBS) with intestinal failure, increasing intestinal wet weight absorption and ...Seidner, Douglas L., Simon M. Gabe, Clément Olivier, Jeppesen, Palle B., Hak-Myung Lee, Olivier, Clément, Palle B. Jeppesen, Douglas L. Seidner, Gabe, Simon M., Lee, Hak Myung +9 morecore +1 more sourceReal-world experience of Teduglutide use in adults with short bowel syndrome: a seven-year international multicenter survey [PDF]
International audienceBackground and aim: Teduglutide is a glucagon-like peptide-2 analogue used to promote intestinal rehabilitation and decrease the dependence from intravenous supplementation (IVS) in patients with short bowel syndrome and intestinal ...Lamprecht, Georg, Cuerda Compes, Cristina, Jezerski, Denise, Schneider, Stéphane, M, Rotovnik Kozjek, Nada, Seguy, David, Gallitelli, Livia, Sasdelli, Anna Simona, Livovsky, Dan M., Schneider, Stephane M., Carey, S, Poullenot, Florian, Sasdelli, Anna S, Taus, Marina, Chapman, Brooke, Aguayo, Pilar Serrano, Itzhaki, Moran Hellerman, Chen, Mona, Hütterer, Elisabeth, Ellegård, Lars,, Martinuzzi, Andrés L N, Boluda, Esther Ramos, Lal, Simon, Aimasso, Umberto, Martins da Rocha, Mariana Hollanda, Orlandoni, Paolo, Maíz Jiménez, María, Vanuytsel, Tim, M Livovsky, Dan, Schneider, Stéphane M, Sobocki, Jacek, Martinuzzi, Andres L. N., Bluethner, Elizabeth, Lopez-Urdiales, Rafael, Lezo, Antonella, Rocha, Mariana Hollanda Martins da, Ellegård, Lars, Bergoin, Charlotte, Maíz-Jiménez, María, Santarpia, Lidia, L N Martinuzzi, Andrés, Zarpellon, Martina, Hellerman Itzhaki, Moran, Layec, Sabrina, Bueno Diez, Marta, Chen, M, Martin, Cristina Campos, Campos Martín, Cristina, Krznaric, Zeljko, Livovsky, Dan M, Kozjek, Nada Rotovnik, Crivelli, Adriana, Osland, Emma, Serrano Aguayo, Pilar, Pelaez, Rosa Burgos, López Urdiales, Rafael, Ramos Boluda, Esther, Blüthner, Elizabeth, Huetterer, Elisabeth, Cuerda, Cristina, Pironi, Loris, Joly, Francisca, H Rasmussen, Henrik, Carey, Sharon, Francini-Pesenti, Francesco, Bezmarević, Mihailo, Gandullia, Paolo, Fehr, Rebecca, Sasdelli, Anna S., Burgos Peláez, Rosa, Sasdelli, Anna, Díez, Marta Bueno, Pape, Ulrich-Frank, Francini Pesenti, Francesco, Regano, Nunzia, Rasmussen, Henrik H., Thibault, Ronan +76 morecore +1 more source