Results 71 to 80 of about 26,029 (200)

A Silkworm Infection Model for In Vivo Study of Glycopeptide Antibiotics

open access: yesAntibiotics, 2020
Glycopeptide antibiotics (GPAs) are drugs of last resort for treating infections by Gram-positive bacteria. They inhibit bacterial cell wall assembly by binding to the d-Ala-d-Ala terminus of peptidoglycan precursors, leading to cell lysis.
Aurora Montali   +7 more
doaj   +1 more source

Biocide tolerance, phenotypic and molecular response of Lactic Acid Bacteria isolated from naturally-fermented Aloreña table olives throughout fermentation to induction by different physico-chemical stresses [PDF]

open access: yes, 2016
Lactic acid bacteria isolated from Aloreña table olives throughout fermentation process were resistant at least to three antibiotics (Casado Muñoz et al., 2014), however they were very sensitive to all biocides tested in this study (MIC below the ...
Abriouel, Hikmate   +5 more
core   +2 more sources

Immunomodulatory Tissue‐Engineering Strategies for Diabetic Foot Ulcer Management: A Systematic Review

open access: yesWound Repair and Regeneration, Volume 34, Issue 2, March/April 2026.
ABSTRACT The aim of this systematic review is to systematically compile evidence from the past 5 years on bioengineering and regenerative medicine approaches targeting the DFU immune microenvironment and to evaluate these findings from a translational perspective to inform clinical applications.
Gözde Özsezer, Yavuz Emre Arslan
wiley   +1 more source

Teicoplanin pharmacokinetics in critically ill patients on extracorporeal organ support: a retrospective analysis

open access: yesIntensive Care Medicine Experimental
Background Extracorporeal membrane oxygenation (ECMO) can alter the pharmacokinetics of diverse antimicrobials, posing challenges in achieving therapeutic drug levels.
Giovanni Camen   +9 more
doaj   +1 more source

A Bifunctional Cytochrome P450 Enzyme Catalyzes Hydroxylation and Aryl‐Aryl Ether Formation in the Biosynthesis of Emestrin

open access: yesChemistry – A European Journal, Volume 32, Issue 7, 16 February 2026.
Conversion of emestrin J (5) to emestrin (1) by three P450 enzymes from the cluster (eme) in Emericella quadrilineata. EmeO acts as a bifunctional enzyme for the construction of the 15‐membered lactone ring via an aryl‐aryl ether bond formation and simultaneous hydroxylation between phenolic and nonphenolic aromatic rings, while EmeE and EmeR install ...
Yu‐Chuan Chen   +3 more
wiley   +1 more source

Impact of teicoplanin maintenance dose and MIC values on the clinical outcomes of patients treated for methicillin-resistant Staphylococcus aureus bacteremia

open access: yesInfection and Drug Resistance, 2018
Ching-Yen Tsai,1 Chen-Hsiang Lee,1,2 Chun-Chih Chien,3 I-Ling Chen4 1Division of Infectious Diseases, Department of Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; 2Chang Gung University College of Medicine, Kaohsiung, Taiwan ...
Tsai CY, Lee CH, Chien CC, Chen IL
doaj  

Emergence of a Teicoplanin-Resistant Small Colony Variant of Staphylococcus epidermidis During Vancomycin Therapy [PDF]

open access: yes, 2018
Small colony variants of Staphylococcus aureus can cause persistent and recurrent infections. There are only a few reports of small colony variants of coagulase-negative staphylococci.
Adler, H., Frei, R., Widmer, A.
core  

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

Optimal Teicoplanin Dosage Regimens in Critically Ill Patients: Population Pharmacokinetics and Dosing Simulations Based on Renal Function and Infection Type

open access: yesDrug Design, Development and Therapy, 2023
Yifan Wang,1,2,* Fen Yao,2,* Shenglong Chen,3 Xin Ouyang,4 Jinhua Lan,5 Zheng Wu,2 Yirong Wang,2 Jingchun Chen,2 Xipei Wang,6,7 Chunbo Chen1 1Department of Critical Care Medicine, Shenzhen People’s Hospital, The Second Clinical Medical College of
Wang Y   +9 more
doaj  

In vitro activity of tigecycline, a new glycylcycline, tested against 1,326 clinical bacterial strains isolated from Latin America [PDF]

open access: yes, 2005
The in vitro activity of tigecycline (former GAR-936), a new semisynthetic tetracycline, was evaluated in comparison with tetracycline and other antimicrobial agents.
Andrade, Soraya Sgambatti   +4 more
core   +2 more sources

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