Results 61 to 70 of about 3,539,647 (271)

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Enerji-GSYH İlişkisine Yeni Bir Bakış: Türkiye ve G7 Ülkelerinde Gelir ve Sürdürülebilir Refah Yaklaşımlarının Karşılaştırılması

Ekonomi, Politika & Finans Araştırmaları Dergisi, 2018
Bu çalışmanın amacı, 2000-2012 döneminde G7 ülkeleri ve Türkiye’de enerji tüketimi-sürdürülebilir refah ilişkisinin analiz edilmesi ve elde edilen bulguların enerji tüketimi-büyüme (gelir) ilişkisiyle karşılaştırılmasıdır.
Mert Topcu, İjlal Tel
doaj   +1 more source

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang, Yuxin Yang, William Martin, Kingsten Lin, Zixu Wang, Cheng‐Chang Lu, Weiwen Jiang, Ruth Nussinov, Joseph Loscalzo, Qiang Guan, Feixiong Cheng   +10 more
wiley   +1 more source

THE PROPERTIES OF THE GROUND STATE OF THE 208Pb AND 209Bi NUCLEI USED ON THE ACCELERATOR DRIVEN SYSTEMS

Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2009
: In this study, by using Hartree-Fock method with an effective nucleon-nucleon Skyrme interactions rms nuclear charge radii, rms nuclear mass radii, rms nuclear proton, neutron radii and neutron skin thickness were calculated for the natPb isotopes and ...
Eyüp TEL
doaj  

Who makes better use of technology for learning in D&T? Schools or university? [PDF]

, 2013
University teacher training departments have many functions in their role as Schools for Initial Teacher Education (ITE), these include accrediting qualified teacher status, teaching subject knowledge and pedagogy, and influencing change in a school ...
Cockayne, S, Davies, S, Hardy, A, Tinney, J   +3 more
core  

Merging and Extending the PGP and PEM Trust Models - the ICE-TEL Trust Model [PDF]

, 1997
The ICE-TEL project is a pan-European project that is building an Internet X.509 based certification infrastructure throughout Europe, plus several secure applications that will use it.
Chadwick, David W., Kapidzic Cicovic, Nada, Young, Andrew J.   +2 more
core   +1 more source

A Female‐Locust‐Inspired Hybrid Soft‐Stiff Robotic Digger: Mimetics and Implications for Digging Efficiency

Advanced Intelligent Systems, EarlyView.
Female desert locusts dig underground to lay their eggs. They displace soil, rather than removing it, to create a tunnel. We analyze burrowing dynamics and 3D kinematics and design a locust‐inspired hybrid soft–stiff robot that reproduces this mechanism. The results show the natural strategy minimizes energy, whereas alternative patterns raise costs up
Shai Sonnenreich, Amir Ayali, Bat‐El Pinchasik   +2 more
wiley   +1 more source

Adware, Shareware, and Consumer Privacy [PDF]

, 2004
Programmers can distribute new software to online users either for a fee as shareware or bundle it with advertising banners and distribute it for free as adware.
Gantman, Nataly - Tel Aviv University, Spiegel, Yossi - Tel Aviv University   +1 more
core   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti, Daniel Souery, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Raffaele Ferri, Giuseppe Fanelli, Chiara Fabbri, Raffaella Zanardi, Francesco Benedetti, Bernhard T. Baune, Julien Mendlewicz   +13 more
wiley   +1 more source

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady, Tova Hershkovitz, Clair Habib, Ori Attias, Amir Hadash, Galit Tal, Asaad Khoury, Josef Ben‐Ari, Danny Eytan, Tamar Paperna, Karin Weiss   +10 more
wiley   +1 more source