Results 61 to 70 of about 12,197 (188)

The Effects Of Telmisartan Neuroprotection On Stroke With Hypertension [PDF]

, 2020
Stroke is the second deadly disease in the world after ischemic heart disease. According to data of RISKESDAS (Riset Kesehatan Dasar), stroke was the highest cause of death in Indonesia in 2013.
Hanik Badriyah Hidayati, Sumarno, Iin Ernawati   +2 more
core   +1 more source

Oxadiazolone‐Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II‐Induced Vascular Contraction

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
A novel series of candidate AT1 receptor antagonists based on oxadiazolone‐triazole scaffolds was designed and synthesized. Most compounds reduced angiotensin II‐induced vascular contraction in an initial biological screening, with compound 7f emerging as the most active derivative.
Larissa F. L. Ferreira, Daiana G. de A. Vasconcelos, Ruth C. A. Santos, Jivaldo G. Ferreira, Alice V. Araújo, Janaína V. dos Anjos   +5 more
wiley   +1 more source

Evaluation of oral telmisartan administration as a suppression test for diagnosis of primary hyperaldosteronism in cats

Journal of Veterinary Internal Medicine, 2023
Background Development of a telmisartan‐based suppression test may facilitate the diagnosis of primary hyperaldosteronism (PHA) in cats, which remains difficult today.
Virginie Fabrès, Renaud Dumont, Mélanie Garcia, Dan Rosenberg, Benoit Rannou, Maxine Kurtz, Ghita Benchekroun   +6 more
doaj   +1 more source

Pembentukan Sistem Biner Telmisartan-Nikotinamida dengan Teknik Solvent Drop Grinding [PDF]

, 2017
Telmisartan adalah obat golongan Angiostensin II Receptor Blocker (ARB) yang digunakan sebagai pengobatan hipertensi. Telmisartan termasuk kelas II berdasarkan Biopharmacetical Classification System (BCS) karena memiliki laju kelarutan yang rendah di ...
Dianty, Novitri
core   +1 more source

Estratégias tecnológicas visando aumentar a solubilidade e o perfil de dissolução da telmisartana [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.A telmisartana (TEL) é um antagonista não peptídico do receptor da angiotensina II do tipo-1 ...
Borba, Paola Aline Amarante
core  

Computational, In Vitro, and In Vivo Evaluation of Benzimidazole–Pyrazole Hybrid Scaffolds as Multi‐Target Anti‐Ulcer Agents

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The hybrid pharmacophore approach involves the combination of benzimidazole‐pyrazole moieties to form multi‐functional anti‐ulcer compounds. Molecular modeling and biological evaluations show significant proton pump inhibition, anti‐inflammatory action, antioxidant property, and remarkable prevention of gastric ulcers.
Hafiz Aamir Ali Kharl, Abdul Malik, Humaira Nadeem, Mohammad Shamsul Ola, Sara Aiman, Arif Ullah Khan, Muhammad Akmal Farooq, Humaira Muzaffar, Syed Muzzammil Masaud   +8 more
wiley   +1 more source

Telmisartan use and risk of dementia in type 2 diabetes patients with hypertension: A population-based cohort study.

PLoS Medicine, 2021
BackgroundAngiotensin receptor blockers (ARBs) may have protective effects against dementia occurrence in patients with hypertension (HTN). However, whether telmisartan, an ARB with peroxisome proliferator-activated receptor γ (PPAR-γ)-modulating effects,
Chi-Hung Liu, Pi-Shan Sung, Yan-Rong Li, Wen-Kuan Huang, Tay-Wey Lee, Chin-Chang Huang, Tsong-Hai Lee, Tien-Hsing Chen, Yi-Chia Wei   +8 more
doaj   +1 more source

Association of the protective effect of telmisartan on hearing loss among patients with hypertension

Frontiers in Neurology
AimHearing loss, affecting a significant portion of the global population, is prevented with peroxisome proliferator-activated receptor γ agonism. Understanding potential protective treatments is crucial for public health.
Jung-Joon Cha, Yunjin Yum, Yong Hyun Kim, Eung Ju Kim, Yoon Chan Rah, Euyhyun Park, Gi Jung Im, Jae-Jun Song, Sung-Won Chae, June Choi, Hyung Joon Joo, Hyung Joon Joo, Hyung Joon Joo   +12 more
doaj   +1 more source

Comparative Study of the Antioxidant Mediated Antiaging Properties of Endocarp Extracts From Phoenix dactylifera and Phoenix dactylifera L. via In Silico and In Vitro Analysis

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This comparative study demonstrates that Phoenix dactylifera possesses higher anti‐aging potential compared to Phoenix dactylifera L., which may be attributed to their higher phenolic and flavonoid contents along with stronger free radical scavenging capacity.
Farheen Asaad, Mazhar Abbas, Waqas Haider, Naveed Munir, Maha Gul Zafar, Muhammad Riaz, Muhammad Arshad, Muhammad Arfan Zaman, Tariq Hussain, Muhammad Adnan Ayub, Hasan Ejaz, Quzi Sharmin Akter   +11 more
wiley   +1 more source

Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant‐Based Therapies: A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam, Umme Halima Mithila, Sadia Alam Tisha, Hridoy Saha, Ayesha Binte Mahbub, Farhan Nizam, Johirul Islam, Noushin Tabasumma, Md. Mazharul Islam Chowdhury   +8 more
wiley   +1 more source