Results 71 to 80 of about 19,704 (200)

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, Volume 4, Issue 1, March 2026.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Association of the protective effect of telmisartan on hearing loss among patients with hypertension

Frontiers in Neurology
AimHearing loss, affecting a significant portion of the global population, is prevented with peroxisome proliferator-activated receptor γ agonism. Understanding potential protective treatments is crucial for public health.
Jung-Joon Cha, Yunjin Yum, Yong Hyun Kim, Eung Ju Kim, Yoon Chan Rah, Euyhyun Park, Gi Jung Im, Jae-Jun Song, Sung-Won Chae, June Choi, Hyung Joon Joo, Hyung Joon Joo, Hyung Joon Joo   +12 more
doaj   +1 more source

The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study [PDF]

, 2017
Aims: Progressive aortic stiffening eventually leads to left ventricular (LV) hypertrophy and heart failure if left untreated. Anti-hypertensive agents have been shown to reverse this to some extent. The effects of sacubitril/valsartan (LCZ696), a dual-
Aichner, Solveig, Albrecht, Diego, Bremerich, Jens, Delles, Christian, Freyhardt, Patrick, Heye, Tobias, Hrabak-Paar, Maja, Janka, Rolf, Keicher, Christian, Khder, Yasser, Langenickel, Thomas, Mayr, Michael, Ott, Christian, Schmieder, Roland E., Wagner, Frank, Yates, Denise   +15 more
core   +1 more source

Prevalence of Hypertension and Its Associated Risk Factors Among Adults in Dinajpur District, Bangladesh: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Hypertension (HTN) is a major non‐communicable disease and a leading risk factor for cardiovascular morbidity and mortality globally. In Bangladesh, regional disparities in HTN prevalence and risk factors remain underexplored.
Most. Nusrat Jahan Resma, Md. Kabir Bin Karim, Shamsuz Zoha, Farhana Hasan, A. S. M. Abu Saeed, Md. Kaderi Kibria   +5 more
wiley   +1 more source

RETRACTED: Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

Ibrain, Volume 12, Issue 1, Page 151-164, Spring 2026.
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju, Samyuktha Villavan, Saranya Ravi, Roja Murugesan, Panneerselvam Theivendren, Vennila Jaganathan, Redlin Jani Rajan, Krupanidhi Karunanithi   +7 more
wiley   +1 more source

Telmisartan Self-Nanoemulsifying Drug Delivery System, Compared With Standard Telmisartan, More Effectively Improves Hepatic Fibrosis in Rats

Dose-Response, 2020
Background: This study was designed to examine effects of telmisartan; an angiotensin receptor blocker; self-nanoemulsifying drug delivery system (SNEDDS) in reversing already-established hepatic fibrosis. Method: Forty rats were given thioacetamide (200
Hussam Murad, Osama Ahmed, Tawfik Ghabrah, Mamdooh Gari   +3 more
doaj   +1 more source

Differential involvement of hippocampal angiotensin 1 receptors in learning and memory processes in bulbectomized rats [PDF]

, 2016
There is conflicting evidence regarding the effect of AT1 receptor antagonists on learning and memory processes. The effects of angiotensin II and losartan administration into CA1 hippocampal area on the avoidance performance in olfactory bulbectomized ...
Belcheva, Iren, Belcheva, Stiliana, Ivanova, Margarita, Tashev, Roman   +3 more
core   +1 more source

Review of ongoing initiatives to improve prescribing efficiency in China; angiotensin receptor blockers as a case history [PDF]

, 2014
Pharmaceutical expenditure is rising by 16% per annum in China and is now 46% of total expenditure. Initiatives to moderate growth include drug pricing regulations and encouraging international non-proprietary name prescribing.
Bennie, Marion, Finlayson, Alexander E, Godman, Brian, Gustafsson, Lars L, Zeng, Wenjie   +4 more
core   +1 more source

Adipose Tissue in SARS‐CoV‐2 Viral Tropism, Viral Replication, and the Concept of a Viral Reservoir: An Update

Obesity, Volume 34, Issue 3, Page 519-523, March 2026.
Adipose tissue as a potential reservoir for and modifier of SARS‐CoV‐2 infection and its complications. Schematic demonstrating the differences in subcutaneous and visceral adipose tissue and infection capacity of SARS‐CoV‐2 with interplay between macrophages and adipocytes as target cells for viral tropism.
Liam Charles Maher, Paul M. Ryan, Noel M. Caplice   +2 more
wiley   +1 more source

The vasodilatory action of telmisartan on isolated mesenteric artery rings from rats [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s): Angiotensin Ⅱ type 1 receptor blockers (ARBs) represent one of the widely used antihypertensive agents. In addition to anti-hypertension effect, some ARBs also show other molecular effects such as activating peroxisome proliferator ...
Xiao-ping Chen, Li-ren Qian
doaj