Results 271 to 280 of about 72,827 (301)

[Telomerase].

Rinsho byori. The Japanese journal of clinical pathology, 2003
Telomerase, an intranuclear enzyme, binds to telomeres at chromosome ends, helps to elongate telomere length and is closely linked to attainment of cellular immortality, a step in carcinogenesis. Since telomerase activity has been detected in several human tumors and hematopoietic malignancies, this enzyme is thought to be a useful marker for cancer ...
Naoki, Tsuji, Naoki, Watanabe
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Telomerases

Annual Review of Biochemistry, 1992
openaire   +2 more sources

Regulation of human telomerase in homeostasis and disease

Nature Reviews Molecular Cell Biology, 2020
Caitlin M Roake, Steven E Artandi, Artandi Steven E   +2 more
exaly  

Telomerase

1995
Abstract In three ciliates and two mammals it has been shown that terminal repeat sequences are synthesized by a specialized DNA polymerase called telomerase (reviewed by Greider 1990; Blackburn 1992). This chapter investigates to what extent the known properties of telomerase are consistent with various features of the terminal repeat ...
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Telomeres and telomerase

Methods, 2017
openaire   +2 more sources

Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe

Cell, 2018
Panagiotis Kotsantis, Valerie Borel, Roberto Bellelli   +2 more
exaly  

Structural Insights into Yeast Telomerase Recruitment to Telomeres

Cell, 2018
Hongwen Chen, Shaohua Shi, Pierre Luciano   +2 more
exaly  

An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1

Cell, 2018
Lu Chen, Caitlin M Roake, Pedro J Batista   +2 more
exaly  

Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres

Cell, 2016
Jens C Schmidt, Arthur J Zaug, Thomas R Cech   +2 more
exaly  

A survey of telomerase activity in human cancer

European Journal of Cancer, 1997
J W Shay, Silvia Bacchetti, Jerry W Shay   +2 more
exaly