Results 161 to 170 of about 128,505 (270)
Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]
"Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A +11 more
core
Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase [PDF]
David K. Cole +16 more
openalex +1 more source
Grandmother Age Effects via Sperm Telomere Length and Egg Telomerase Transcripts
ABSTRACT The Lansing effect is a transgenerational age effect by which old parents tend to produce less viable descendants. Despite its importance for the evolution of lifespan and parental effects, the transgenerational nature of age effects and the underlying mechanisms are poorly understood.
Sin‐Yeon Kim +2 more
wiley +1 more source
Evidence for a Relief of Repression Mechanism for Activation of the Human Telomerase Reverse Transcriptase Promoter [PDF]
Shuwen Wang, Jiyue Zhu
openalex +1 more source
ABSTRACT Telomeres, repetitive nucleotide sequences at chromosome ends, shorten with oxidative damage and cell replication, and are increasingly used as biomarkers of stress and physiological state. Despite this potential, telomere length (TL) in marine mammals has been measured using Southern blot hybridization in only a few cases, often from ...
Haruka Nakajin +10 more
wiley +1 more source
A polymorphism of DSP was associated with prognosis and acute exacerbation in Japanese individuals with idiopathic pulmonary fibrosis (IPF), and a polymorphism of TERT was associated with prognosis in the patients with IPF and acute exacerbation in those with unclassifiable idiopathic interstitial pneumonias, indicating the potential of personalised ...
Kazuya Tsubouchi +18 more
wiley +1 more source
Health Benefits and Therapeutic Potential of Quercetin
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley +1 more source

