Results 141 to 150 of about 28,516 (233)

Control of gene expression in prostate epithelial cell differentiation hierarchy [PDF]

, 2012
The aim of present investigation is to elucidate the complex stem cell (SC) dynamics within prostate cancer, which can be exploited to design novel diagnostic and therapeutic strategies for the management of prostate cancer.
Rane, Jayant
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Telomerase Reverse Transcriptase and Wnt Signaling [PDF]

Molecular and Cellular Biology, 2011
openaire   +2 more sources

Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria.

, 2011
Human telomerase reverse transcriptase (hTERT) is localized to mitochondria, as well as the nucleus, but details about its biology and function in the organelle remain largely unknown.
Nilesh K. Sharma (8037197), Marcelo G. Bonini, Ian J. Holt, Janine Hertzog Santos, Aurelio Reyes (412135), Nilesh K. Sharma, Matthieu J. Caron (8037200), Paula Green (2335621), Ian J. Holt (8037203), Janine Hertzog Santos (8037206), Matthieu J. Caron, Donna M. Gordon, Paula Green, Marcelo G. Bonini (7921832), Aurelio Reyes, Donna M. Gordon (795108)   +15 more
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Cancer immunotherapy targeting the telomerase reverse transcriptase.

, 2006
The human telomerase reverse transcriptase (hTERT) is expressed in more than 85% of tumor cells but is usually not found in normal cells, which makes hTERT as an ideal tumor-associate antigen (TAA) to develop potential vaccine specifically destroying ...
Lin, MC, Tang, JW, Kung, HF, Huo, LF, Huang, JJ, Huang, CF, Huang, PT   +6 more
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Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo.

, 2009
BACKGROUND:Telomerase is a reverse transcriptase that maintains the telomeres of linear chromosomes and preserves genomic integrity. The core components are a catalytic protein subunit, the telomerase reverse transcriptase (TERT), and an RNA subunit, the
Beattie Tara L., Wyatt Haley D. M., Haley D M Wyatt, Tsang Allison R., Lobb Deirdre A., Allison R. Tsang, Tara L Beattie, Haley D. M. Wyatt, Tara L. Beattie, Allison R Tsang, Deirdre A Lobb, Deirdre A. Lobb   +11 more
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The Biological and Clinical Role of the Telomerase Reverse Transcriptase Gene in Glioblastoma: A Potential Therapeutic Target? [PDF]

Cells, 2023
Di Nunno V, Aprile M, Bartolini S, Gatto L, Tosoni A, Ranieri L, De Biase D, Asioli S, Franceschi E.   +8 more
europepmc   +1 more source

Novel telomerase reverse transcriptase gene mutation in a family with aplastic anaemia

Telomerase Reverse Transcriptase (TERT) encodes the telomerase reverse transcriptase enzyme and is the most frequently mutated gene in patients with telomeropathies.
Anđelković, Marina, Micic, D., Jakovic, Lj, Bogdanovic, A., Pavlović, Sonja, Virijevic, M., Marjanović, Irena   +6 more
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Telomerase reverse transcriptase (TERT) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Telomerase reverse transcriptase (TERT) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Telomerase is a true reverse transcriptase. A review

Synthesis of telomeric repeats at chromosome ends requires telomerase, a ribonucleoprotein enzyme. The RNA subunit, which contains the template for DNA synthesis, has been identified in many organisms.
Cech, T. R., Nakamura, T. M., Lingner, J.   +2 more
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