Results 291 to 300 of about 85,495 (318)

Telomere biology in neuroblastoma: telomere binding proteins and alternative strengthening of telomeres

Journal of Pediatric Surgery, 2009
Neuroblastoma (NBL) shows remarkable biologic heterogeneity, resulting in favorable or unfavorable prognoses. Previously, we reported that most unfavorable NBLs express high telomerase activity to maintain telomere length. Recently, telomere binding proteins (TBPs) and alternative lengthening of telomeres (ALTs) have been identified as key factors of ...
Yoshiyuki, Onitake, Eiso, Hiyama, Naomi, Kamei, Hiroaki, Yamaoka, Taijiro, Sueda, Keiko, Hiyama   +5 more
openaire   +2 more sources

Characterization and expression analysis of the tomato telomere-binding protein LeTBP1

Plant Science, 2006
Abstract We cloned LeTBP1 cDNA that encoded a putative tomato telomere-binding protein. Sequence analysis revealed that LeTBP1 contained an open reading frame of 2067 bp and encoded a protein consisting of 689 amino acids with a predicted molecular mass of 77.0 kDa. The deduced amino sequence of LeTBP1 indicated that a myb-like motif, a structure
Ryo Moriguchi, Koki Kanahama, Yoshinori Kanayama   +2 more
openaire   +1 more source

Phosphorylation of Mitochondrial Telomere Binding Protein ofCandida parapsilosisby Camp-Dependent Protein Kinase

Biochemical and Biophysical Research Communications, 1998
Mitochondrial telomere-binding protein (mtTBP) of Candida parapsilosis binds with high affinity to 5' single-stranded overhang of the linear mitochondrial DNA of this yeast (Tomáska, L'., Nosek, J., and Fukuhara, H. (1997) J. Biol. Chem. 272, 3049-3056).
openaire   +2 more sources

Analysis of telomere replication activities: telomerase and telomere binding proteins

1999
Abstract This chapter outlines the types of assays currently available for the analysis of two major classes of proteins important for telomere replication: telomerase, and telomere binding proteins. Since many of the other activities important for telomere replication, including DNA polymerases and helicases, are not necessarily ...
openaire   +1 more source

Structure of active human telomerase with telomere shelterin protein TPP1

Nature, 2022
Baocheng Liu, Yao He, Yaqiang Wang
exaly  

Telomerase and telomere-binding proteins: Controlling the endgame

Trends in Biochemical Sciences, 1997
openaire   +3 more sources

Ruolo del TRF1 (Telomere Binding Protein 1) nei tumori umani.

2003
CNR, ROMA. 7/8 febbraio 2003. (Relazione orale) - ISSN:
ARAGONA, Marcello, PANETTA S, MORELLI M, BUDA CA, LA TORRE, Domenico, CAMPAGNA FL, LA TORRE F.   +6 more
openaire   +1 more source

Regulation of telomere length and function by a Myb-domain protein in fission yeast

Nature, 1997
Julia Promisel Cooper, Elaine R Nimmo, Thomas R Cech   +2 more
exaly  

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

Nature, 2012
Jayakrishnan Nandakumar, Caitlin F Bell, Thomas R Cech   +2 more
exaly  

POT1 as a terminal transducer of TRF1 telomere length control

Nature, 2003
Diego Loayza, Titia de Lange
exaly