Results 231 to 240 of about 110,933 (294)

Hepatic FGF21 Deletion Improves Glucose Metabolism, Alters Lipogenic and <i>Chrna4</i> Gene Expression, and Enhances Telomere Maintenance in Aged Female Mice. [PDF]

Int J Mol Sci
Torres-Oteros D, Nicola-Llorente M, Sanz-Lamora H, Pérez-Martí A, Marrero PF, Canudas S, Haro D, Relat J.   +7 more
europepmc   +1 more source

Clinical Characteristics and Evolution of Interstitial Lung Disease in Subtypes of Idiopathic Inflammatory Myositis With Prevalent Lung Manifestation: A Retrospective Analysis

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation‐associated protein 5 (anti‐MDA5) syndrome, and scleromyositis. ILD can progress despite resolution of extrapulmonary symptoms, termed postmyopathic progressive pulmonary fibrosis ...
Julia Clark, Dora Chan, Damon Dhillon, Jan Dutz, Gillian Goobie, Kun Huang   +5 more
wiley   +1 more source

Maternal smoking during pregnancy and newborn telomere length (TL): a systematic review and meta-analysis of observational studies. [PDF]

BMC Pregnancy Childbirth
Moshfeghinia R, Ghahremani M, Ghasemi AR, Mostafavi S, Mohagheghzadeh H, Maharlouei N, Ahmadi J, Vardanjani HM.   +7 more
europepmc   +1 more source

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

Engineering Immortalized Bovine Granulosa Cells Using a Triple‐Gene Approach: Mutant CDK4, Cyclin D1, and TERT

Cell Biology International, Volume 50, Issue 2, February 2026.
ABSTRACT Advancing reproductive technologies in livestock is essential to improve both productivity and genetic potential of cattle. Despite this importance, application of reproductive biotechnologies in cattle breeding remains limited. Bovine granulosa cells (bGCs), which are key components of the ovarian follicle, are critical in female reproduction
Lanlan Bai, Minami Takahashi, Jin Kobayashi, Takahiro Eitsuka, Himari Matsusaka, Taku Ozaki, Eriko Sugano, Hiroshi Tomita, Yuan Xu, Kazuhiro Kawamura, Kiyotaka Nakagawa, Tohru Kiyono, Tomokazu Fukuda   +12 more
wiley   +1 more source

Colon Organoids as Experimental Models to Study the Effect of Micro-Nanoparticles as a Driver of Early-Onset Colon Cancer. [PDF]

Cells
Heydari Z, Sarkar G, Helgeson L, Cruz Garcia EM, Ros A, Khazaie K, Boardman L.   +6 more
europepmc   +1 more source

Science of omics: a molecular space odyssey

Experimental Physiology, EarlyView.
Salomé Coppens, Christophe Hirtz, Margaux Vignon, Damian M. Bailey   +3 more
wiley   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, Volume 158, Issue 3, Page 642-655, 1 February 2026.
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

Targeting telomere dynamics with plant-derived compounds: Molecular strategies against aging. [PDF]

Curr Res Pharmacol Drug Discov
Akter R, Bishakha AC, Rajib R, Raj A, Roja MS, Noor F.   +5 more
europepmc   +1 more source

Noninvasive Early Detection and Recurrence Monitoring for Non‐Muscle‐Invasive Bladder Cancer via Urine Tumor DNA: A Prospective Clinical Study

MedComm, Volume 7, Issue 2, February 2026.
In NMIBC surveillance, positive postoperative utLIFE‐UC results before initial follow‐up cystoscopy were significantly associated with increased relapse risk. Longitudinal analysis showed that positive utLIFE‐UC results at any time after TURBT correlated with worse recurrence‐free survival, while sustained negative results predicted recurrence‐free ...
Junlong Wu, Shengming Jin, Qianming Bai, Huina Wang, Huanqing Cheng, Xiaoyan Zhou, Yijun Shen, Chunguang Ma, Chengyuan Gu, Hui Chen, Yafeng Zhang, Libin Chen, Shahrokh F. Shariat, Feng Lou, Shanbo Cao, Yiping Zhu, Dingwei Ye   +16 more
wiley   +1 more source