Results 241 to 250 of about 110,933 (294)

Genetic Determinants of Progressive Pulmonary Fibrosis: A Comprehensive Review. [PDF]

open access: yesInt J Mol Sci
Zhumagaliyeva A   +2 more
europepmc   +1 more source

The physiology of survival: Space

open access: yes
Experimental Physiology, EarlyView.
Damian M. Bailey, Angelique van Ombergen
wiley   +1 more source

From Permits to Samples: Addressing Key Challenges for High‐Quality Reference Genome Generation in Europe

open access: yesMolecular Ecology Resources, Volume 26, Issue 2, February 2026.
ABSTRACT High‐quality reference genome assemblies have become essential for deepening our understanding of biodiversity, yet obtaining them for many species remains surprisingly challenging. Drawing on experiences from the European Reference Genome Atlas (ERGA) community, we focus on permit and sample‐handling procedures leading up to nucleic acid ...
Katja Reichel   +32 more
wiley   +1 more source

BLM and FANCJ role in the response to G-quadruplex-dependent telomeric replicative stress. [PDF]

open access: yesCommun Biol
Bonanni L   +6 more
europepmc   +1 more source

A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng   +14 more
wiley   +1 more source

Large-scale drug sensitivity, gene dependency, and proteogenomic analyses of telomere maintenance mechanisms in cancer cells. [PDF]

open access: yesNat Commun
Wu Y   +21 more
europepmc   +1 more source

Astronauts as a Human Aging Model: Epigenetic Age Responses to Space Exposure

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This longitudinal analysis of Axiom‐2 astronauts reveals that spaceflight induces a rapid andsignificant epigenetic age acceleration that is largely reversible upon return to Earth. These findings identify space exposure as a unique model for studying aging mechanisms and potentially testing geroprotective interventions.
Matías Fuentealba   +6 more
wiley   +1 more source

Comparison of the effectiveness of Models 1, 2a and 2b in estimating fetal fraction (FF) based on telomere content.

open access: green
Zuzana Holesova (15253816)   +7 more
openalex   +1 more source

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