Results 241 to 250 of about 110,933 (294)
Genetic Determinants of Progressive Pulmonary Fibrosis: A Comprehensive Review. [PDF]
Zhumagaliyeva A +2 more
europepmc +1 more source
Leukocyte Telomere Length and Polycystic Ovary Syndrome: A Transethnic Mendelian Randomization Study
Lan Cao, Jie Chen
openalex +1 more source
The physiology of survival: Space
Experimental Physiology, EarlyView.
Damian M. Bailey, Angelique van Ombergen
wiley +1 more source
ABSTRACT High‐quality reference genome assemblies have become essential for deepening our understanding of biodiversity, yet obtaining them for many species remains surprisingly challenging. Drawing on experiences from the European Reference Genome Atlas (ERGA) community, we focus on permit and sample‐handling procedures leading up to nucleic acid ...
Katja Reichel +32 more
wiley +1 more source
BLM and FANCJ role in the response to G-quadruplex-dependent telomeric replicative stress. [PDF]
Bonanni L +6 more
europepmc +1 more source
A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng +14 more
wiley +1 more source
Large-scale drug sensitivity, gene dependency, and proteogenomic analyses of telomere maintenance mechanisms in cancer cells. [PDF]
Wu Y +21 more
europepmc +1 more source
Astronauts as a Human Aging Model: Epigenetic Age Responses to Space Exposure
This longitudinal analysis of Axiom‐2 astronauts reveals that spaceflight induces a rapid andsignificant epigenetic age acceleration that is largely reversible upon return to Earth. These findings identify space exposure as a unique model for studying aging mechanisms and potentially testing geroprotective interventions.
Matías Fuentealba +6 more
wiley +1 more source

