Results 251 to 260 of about 110,933 (294)

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits

Aging Cell, Volume 25, Issue 2, February 2026.
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen, Jennifer L. Martindale, Martina Rossi, Chang Hoon Shin, Apala Pal, Rachel Munk, Martin Salamini‐Montemurri, Mirko Baranzini, Ethan M. Arends, Maja Mustapic, Yuta Lee, Jau‐Nan Lee, Sicco H. Popma, Justin Hu, Nathan Duda, Carlos J. Nogueras‐Ortiz, Dimitrios Kapogiannis, Chang‐Yi Cui, Myriam Gorospe   +18 more
wiley   +1 more source

TelOMpy enables single-molecule resolution of telomere length from optical genome mapping data. [PDF]

BMC Biol
Pokrovac I, Stipoljev S, Pezer Ž.
europepmc   +1 more source

Telomere length and metabolic dysfunction-associated steatotic liver disease risk and progression: A systematic review and meta-analysis

Chunfeng Sun, Ping Qiu, Shuo Huang, Qihan Luo, Qing Ma, Piao Hu, Ping Qiu, Hongyan Wu, Chunxiao Chen   +8 more
openalex   +1 more source

Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice

Aging Cell, Volume 25, Issue 2, February 2026.
Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang, Yu‐Jie Chen, Yu‐Xin Hu, Jia‐Chen Liu, Min Hu   +4 more
wiley   +1 more source

Reversine-Induced Telomere Architecture Remodeling in Chronic Myeloid Leukemia Cell Lines: Insights from TeloView^® Analysis of 3D Nuclear Architecture. [PDF]

Curr Issues Mol Biol
Morato de Oliveira F, Cruvinel ID, Ferreira BMR, Mai S.   +3 more
europepmc   +1 more source

Grandmother Age Effects via Sperm Telomere Length and Egg Telomerase Transcripts. [PDF]

Mol Ecol
Kim SY, Chiara V, Velando A.
europepmc   +1 more source

Osmotic pressure regulates DNA labelling and transcription with dCas9-SunTag system in live cells. [PDF]

Nat Commun
Wei T, Yang X, Jiang C, Liao K, Ye H, Luo HY, Liu YR, Wang PY, Meng F, Dou SX, Rong Z, Li H.   +11 more
europepmc   +1 more source

Transcriptional regulation of telomeric repeat-containing RNA by the G-quadruplex-binding Ewing sarcoma protein. [PDF]

Sci Rep
Ulum LL, Matsudaira W, Yamanashi M, Shibata N, Saha S, Ishihara A, Oyoshi T.   +6 more
europepmc   +1 more source

CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres

Lanna A, Valvo S, Dustin ML, Rinaldi F.
europepmc   +1 more source