Results 131 to 140 of about 61,558 (234)

Dual-drug delivery system based on cubosomes for glioblastoma therapy: electrochemical, structural and biological characterization. [PDF]

Nanoscale Adv
Dąbrowska E, Gaweł D, Godlewska M, Gajda E, Bilewicz R, Nazaruk E.   +5 more
europepmc   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 2986-3001, September 2026.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

No association between temozolomide maintenance and survival after first-line treatment in primary CNS lymphoma. [PDF]

Hemasphere
Chowdhury N, Niemi J, Babačić H, Rantakylö HM, Glimelius I, Jerkeman M, Hellström M.   +6 more
europepmc   +1 more source

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +1 more source

ERP44 Is Associated With Poor Prognosis and Promotes Proliferation and Temozolomide Resistance in Lower-grade Glioma. [PDF]

Cancer Genomics Proteomics
Shao L, Liu J, Amin MR, Jian Z.
europepmc   +1 more source

POFUT1 Serves as an Independent Prognostic Factor and Therapeutic Target by Activating the PI3K/AKT Pathway in Glioma

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective Protein O‐fucosyltransferase 1 (POFUT1) has been implicated in several malignancies, but its functional and prognostic significance in glioma remains insufficiently defined. This study evaluated whether POFUT1 expression is associated with glioma progression, patient outcome, and PI3K/AKT pathway activity.
Kai Yang, Chunlei Ju, Yifan Wang, Aijie Guo, Xiaochen Yang, Yang Mi, Yifei Su, Chunhong Wang, Hongming Ji   +8 more
wiley   +1 more source

Nasal NUT carcinoma with repeated responses during multimodal treatment incorporating radiotherapy: A case report. [PDF]

Medicine (Baltimore)
An Q, Tao Y, Wang P, Wang Z.
europepmc   +1 more source

Study of Adaptive Radiotherapy for High‐Grade Glioma Based on Interfraction MRI

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Currently, there is no clear guidance on the appropriate population or timing for adaptive radiotherapy (ART) in high‐grade glioma (HGG) patients. This study aims to provide individualized ART for HGG patients. Methods Participants received standard “radiotherapy combined with temozolomide” and underwent MRI before radiotherapy (FX0)
Shuangshuang He, Hang Yu, Yuan Yang, Qing Mao, Xiang Wang, Yunhui Zeng, Feng Wang, Mengyuan Liu, Yuantai Li, Kun Gao, Xingchen Peng, Yanhui Liu, Ping Ai   +12 more
wiley   +1 more source

Redefining the Role of Chemotherapy and Targeted Cytotoxic Delivery in Lung Neuroendocrine Tumors. [PDF]

Thorac Cancer
Laffi A, Lamberti G, La Salvia A.
europepmc   +1 more source

Spatial Omics in High‐Grade Gliomas: Mapping Immune–Tumor Niches for Precision Therapy

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT High‐grade gliomas (HGGs), particularly glioblastoma (GBM), remain among the most lethal human cancers despite decades of molecular profiling and therapeutic innovation. A primary reason for treatment failure is that HGG biology is spatial: malignant cell states, immune suppression, metabolic stress, and therapeutic resistance are organized ...
Saniyah Shaikh, Thaabit Raziq, Sulaf B. Alfares, Touleen T. Raslan, Ismail A. Abdullah, Itika Arora, Shamsa Saleh, Mohammed Imran Khan, Ahmed Yaqinuddin   +8 more
wiley   +1 more source