Results 81 to 90 of about 4,483,408 (274)

Green Compact Temperature Evolution during Current-Activated Tip-Based Sintering (CATS) of Nickel

Metals, 2013
Current-activated tip-based sintering (CATS) is a novel process where spark plasma sintering conditions are applied through an electrically conducting tip on a locally controlled area on a green powder compact/bed. The localization of electric current in
Khaled Morsi, Samuel K. Kassegne, Ahmed El Desouky, Kee S. Moon   +3 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Finite-Element Model Based Distribution Calculations of Current and Temperature within a DC Overhead Catenary

Вестник Научно-исследовательского института железнодорожного транспорта, 2015
There is proposed finite-element model of current/temperature distribution in a DC overhead catenary and are described basic principles of its generation.
A. V. Paranin
doaj  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Research on Dynamic Reduced‐Order Model for Fast Calculation of Transient Temperature Field in Transformer Windings

IET Electric Power Applications
To mitigate the potential loss of computational accuracy in the Reduced‐Order Model (ROM) due to modal changes during transformer operation, this paper proposes a dynamic updating method for the ROM.
Kexin Liu, Dongyang Li, Yunpeng Liu, Gang Liu, Zhenbin Du, Shuqi Zhang, Ke Wang, Xiaolin Zhao   +7 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Structural optimisation of oil immersed transformer winding block washers based on WOA‐DRBF surrogate model optimisation strategy

IET Electric Power Applications
In order to reduce the transformer winding hot spot temperature (HST), a dynamic radial basis function surrogate model optimisation strategy is proposed to optimise the structure of the forced oil circulation transformer winding's block washers in this ...
Yufei Dong, Chenglong Gao, Wenxin Xiang, Gang Liu, Yunpeng Liu, Yang Liu, Zhenbin Du   +6 more
doaj   +1 more source

Design Optimization of Direct Combustion Process in Regenerative Thermal Oxidizer at Low Concentration of Coal Mine Gas Using Advanced Computational Models

Fluids
Coal mine gas with methane concentrations below 8% cannot sustain stable self-combustion, posing significant challenges for safe utilization and greenhouse gas mitigation.
Jida Zhang, Dong Wang, Zhongkuan Wei, Sheng Li, Junhui Yang, Shiyang Jia, Zhongcheng Ma, Chengmin Chen, Krishnaswamy Nandakumar   +8 more
doaj   +1 more source

Numerical simulation of exciton dynamics in Cu2O at ultra low temperatures within a potential trap

, 2012
We have studied theoretically the relaxation behaviour of excitons in cuprous oxide (Cu2O) at ultra low temperatures when excitons are confined within a potential trap by solving numerically the Boltzmann equation.
Ashcroft N W, Frank Kieseling, Heinrich Stolz, Moskalenko S A, O’Hara K E, Pethick C J, Schwartz R, Sunipa Som, William E S   +8 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source