Results 41 to 50 of about 1,273,672 (267)

Electromagnetic-thermal multi-physics coupling simulation of cable joints: considering contact resistance and typical defects

Frontiers in Energy Research
As the “artery” of the urban power grid, high-voltage cables and their operating status are directly related to grid safety. Cable joint is a weak part of cable line prone to defects, leading to cable failure and jeopardizing the power supply reliability.
Lifang Wu, Qingren Jin, Xiaoyong Yu, Biyun Zhang   +3 more
doaj   +1 more source

Numerical and Experimental Reconstruction of Temperature Distribution and Soot Concentration Field for Thin-Slice Flames Using a Charge Coupled Device Camera

Fire, 2023
This work proposed a novel model to simultaneously reconstruct temperature distribution and soot volume fraction field for two-dimensional thin-slice flames using the knowledge of monochromatic radiation intensities at two wavelengths using a CCD camera.
Mingfei Chen, Yun Chen, Tianjiao Li, Dong Liu   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Online Monitoring Based on Temperature Field Features and Prediction Model for Selective Laser Sintering Process

Applied Sciences, 2018
Selective laser sintering (SLS) is an additive manufacturing technology that can work with a variety of metal materials, and has been widely employed in many applications.
Zhehan Chen, Xianhui Zong, Jing Shi, Xiaohua Zhang   +3 more
doaj   +1 more source

Fire Effect and Performance of Bridge Pylon Columns under Construction

Fire, 2023
The fire effect and performance of bridge pylons under construction were investigated via an analysis conducted on two types of pylons with different wall thicknesses. Three fire scenarios, namely internal fire, external ring fire, and external side fire,
Yang Li, Zuocai Wang, Changjian Wang, Yin Zhang, Hongsheng Ma, Lili Liu   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Numerical Simulation of Zr-based Bulk Metallic Glass During Continuous Casting Solidification Process [PDF]

Materials Research, 2015
A numerical simulation method was used to analyze the solidification process of Zr-based bulk metallic glass (BMG) during the horizontal continuous casting (HCC) process.
Renhong Tang, Bingwen Zhou, Yuejiao Ma, Fei Jia, Xingguo Zhang   +4 more
doaj   +2 more sources

A New Multi-Physics Coupled Method for the Temperature Field of Dry Clutch Assembly

Applied Sciences, 2023
The temperature field of the clutch assembly is critical for the clutch design and operation life. Current modeling methods of the temperature of the clutch assembly suffer from insufficient accuracy or a limited time scale for the complicated multi ...
Jun Chen, Jiali Yu, Yubing Gong
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Influence of angle adjustment of theoutlet blade on thermal comfort

Zhileng xuebao, 2020
The correct outlet blade angle can maximize the capacity of an air-conditioning system and effectively improve the flow field and temperature distribution in the car, thereby greatly improving the thermal comfort of passengers.
Li Siwang, Li Shuai, Feng Hongfei
doaj