Results 51 to 60 of about 1,270,960 (266)

A New Multi-Physics Coupled Method for the Temperature Field of Dry Clutch Assembly

Applied Sciences, 2023
The temperature field of the clutch assembly is critical for the clutch design and operation life. Current modeling methods of the temperature of the clutch assembly suffer from insufficient accuracy or a limited time scale for the complicated multi ...
Jun Chen, Jiali Yu, Yubing Gong
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Simulation and Optimization of Large Broiler House

Journal of Harbin University of Science and Technology, 2017
For the broiler house poorly ventilated and the problem of uneven temperature distribution， numerical simulation method was used，the grid was partitioned by Icem，the equation was solved by the steady state solution by Fluent，and then grid-independent ...
WANG Fang, XU Hong-xiang, CUI Lu-lu
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Numerical simulation of temperature field in core storage of ocean exploration vessel

Zhongguo Jianchuan Yanjiu, 2020
Objectives This study is focused on whether CFD can be used to analyze the temperature distribution in the core storage of ocean exploration vessels.Methods In the core storage of ocean exploration vessels, high-temperature storage is 4℃, low-temperature
GUO Yuejiao, WU Yihao, MA Shuang, CHEN Xu, MENG Bo, LEI Shuya, SHI Dachuan, FENG Guozeng   +7 more
doaj   +1 more source

Finite-temperature retarded and advanced fields [PDF]

Nuclear Physics B, 1998
By employing retarded and advanced propagators, Aurenche and Becherrawy showed how to rewrite the real-time thermal Feynman rules so that the temperature dependence is removed from the free propagators and transferred to the vertices. The present paper introduces retarded and advanced field operators and incorporates all temperature dependence into the
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Formation laws and mechanism of freezing temperature fields of multiple coil tubes under groundwater seepage conditions

Meikuang Anquan
In order to study the formation law of artificial frozen temperature field and the formation mechanism of frozen wall in deep alluvial layer under the action of groundwater seepage, the paper analyzes the spatiotemporal evolution law of frozen ...
Chuanxin RONG, Runze ZHANG, Wei LONG, Shiqing HUANG, Jihao FENG   +4 more
doaj   +1 more source

Medley in finite-temperature field theory [PDF]

Canadian Journal of Physics, 1993
Three subjects in thermal field theory are discussed; why in SU(N) gauge theories the Z(N) symmetry is broken at high (instead of low) temperature, the possible singularity structure of gauge-variant propagators, and the problem of how to compute the viscosity from the Kubo formula.
openaire   +2 more sources