Results 61 to 70 of about 703,170 (308)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Design and Research of Air-core Reactor for Middle-low-speed Maglev Train

open access: yes机车电传动, 2012
Development of air-core reactor for middle-low-speed maglev train was introduced. Key technology of air-core reactor was described, inductance calculation, structure design, temperature-rising and shielding-plate calculation of which were analyzed in ...
WU Fu-Lian   +4 more
doaj  

Shear Bond Strength and Temperature Rise of Orthodontic Brackets Bonding by Using a New 3-Second LED Mode

open access: yesTurkish Journal of Orthodontics, 2013
Objective:The aim of this study was to evaluate the effects of different curing times of a light-emitting diode (LED) on the bond strength of stainless steel brackets and to evaluate the temperature changes in the pulp chamber during curing of the ...
Ahmet Yagci   +1 more
doaj   +1 more source

V. On the expansion of porcelain with rise of temperature [PDF]

open access: yesThe London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 1899
n ...
openaire   +4 more sources

Falling for Rising Temperatures?: finance in a carbon-constrained world [PDF]

open access: yes, 2020
Mitigating climate change requires significant societal change. But global action to keep temperature rise within safe bounds is still highly deficient. A heated debate exists about the role that firms and financial markets play in contributing to a solution.
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Evaluation of Lithium Battery Cycle Aging Based on Temperature Increase During Charging

open access: yesBatteries
This study investigates the temperature increase characteristics of lithium-ion batteries under various states of health (SOHs) and proposes an aging assessment method based on temperature increase.
Hanchi Hong   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Experiment and Modeling of Smoke Ventilation in a Compartment using Coconut Husks as Solid Fuels

open access: yesInternational Journal of Technology
Modern architecture has become increasingly attractive and intriguing, with huge rooms and high ceilings. A 1:10 reduced-scale experimental compartment size 2.4 m x 1.6 m x 1.0 m has two floors with a mezzanine constructed.
Beline Alianto   +4 more
doaj   +1 more source

Rising Tempers, Rising Temperatures

open access: yes, 2016
Section one of the papers provides a brief overview of the relationship between the Sahel region of Africa and climate variability trends and predictions, ultimately posing the primary research question of the study: Is the Sahel region more likely to have a higher probability of conflict and migration as a result of climate change and climate change ...
openaire   +1 more source

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