Results 61 to 70 of about 1,113,211 (316)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Urea granule dissolution in soil and soil urease activity are essential parameters for the accurate prediction of nitrogen dynamics after urea application, but both are scarcely studied. The response of urease activity to temperature is unclear under the
Kang Ni, Andreas Siegfried Pacholski
doaj +1 more source
Millennial temperature reconstruction intercomparison and evaluation [PDF]
There has been considerable recent interest in paleoclimate reconstructions of the temperature history of the last millennium. A wide variety of techniques have been used.
J. Esper +26 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Thermosensitivity experiments and simulation calculations were conducted on typical oil sand core samples from Kinosis, Canada to predict the steam chamber development with time-lapse seismic data during the steam-assisted gravity drainage (SAGD).
Yunfeng GAO +6 more
doaj +1 more source
Batch fermentation process: Modelling and direct sensitivity analysis [PDF]
Based on a nonlinear model, this article realizes an investigation of dynamic behaviour of a batch fermentation process using direct sensitivity analysis (DSA).
Sipos, Anca +11 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Design of Current Equalization Circuit in Dual Ethernet Power Supply System
A current-balancing circuit for a dual-channel Ethernet power supply system is designed in this paper, which can be used to solve the mismatch between the two channels caused by unavoidable factors, such as mismatched resistances, temperatures and ...
Xingyu Guan +3 more
doaj +1 more source
Climate change detection and attribution: Beyond mean temperature signals [PDF]
A significant influence of anthropogenic forcing has been detected in global- and continental-scale surface temperature, temperature of the free atmosphere, and global ocean heat uptake.
Xuebin Zhang +23 more
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

