Results 71 to 80 of about 16,749,992 (355)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

On quantifying the apparent temperature sensitivity of plant phenology.

New Phytologist, 2019
•Many plant phenological events are sensitive to temperature, leading to changes in the seasonal cycle of ecosystem function as the climate warms. To evaluate the current and future implications of temperature changes for plant phenology, researchers ...
T. Keenan, A. Richardson, K. Hufkens
semanticscholar   +1 more source

Upper temperature limits of tropical marine ectotherms: global warming implications [PDF]

, 2011
Animal physiology, ecology and evolution are affected by temperature and it is expected that community structure will be strongly influenced by global warming.
Peck, Lloyd S., Tan, Koh Siang, Lloyd S Peck, Lai Chien-Houng, Lai, Chien-Houng, Simon A Morley, Melody S Clark, Chien-Houng Lai, Clark, Melody S., Lai, C.-H., Morley, Simon A., Nguyen Khanh Dung T., Tan Koh Siang, Tan, K.S., Khanh Dung T Nguyen, Clark, M.S., Bates, Amanda E., Bates, A.E., Bates Amanda E., Clark Melody S., Peck Lloyd S., Koh Siang Tan, Nguyen, K.D.T., Peck, L.S., Amanda E Bates, Morley Simon A., Nguyen, Khanh Dung T., Morley, S.A.   +27 more
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Temperature sensitivity of decomposition decreases with increasing soil organic matter stability.

Science of the Total Environment, 2019
Evaluation of the temperature sensitivity of soil organic matter (SOM) decomposition is critical for forecasting whether soils in a warming world will lose or gain carbon and, therefore, accelerate or mitigate climate warming.
G. Moinet, M. Moinet, J. Hunt, C. Rumpel, A. Chabbi, P. Millard   +5 more
semanticscholar   +1 more source

PCF Based Sensor with High Sensitivity, High Birefringence and Low Confinement Losses for Liquid Analyte Sensing Applications [PDF]

, 2015
In this paper, we report a design of high sensitivity Photonic Crystal Fiber (PCF) sensor with high birefringence and low confinement losses for liquid analyte sensing applications.
Huseyin Ademgil, Haxha, Shyqyri, Ademgil, Huseyin, Shyqyri Haxha   +3 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Soil Moisture and Temperature Effects on Granule Dissolution and Urease Activity of Urea with and without Inhibitors—An Incubation Study

Agriculture, 2022
Urea granule dissolution in soil and soil urease activity are essential parameters for the accurate prediction of nitrogen dynamics after urea application, but both are scarcely studied. The response of urease activity to temperature is unclear under the
Kang Ni, Andreas Siegfried Pacholski
doaj   +1 more source

High temperature sensitivity of Arctic isoprene emissions explained by sedges. [PDF]

Nat Commun
It has been widely reported that isoprene emissions from the Arctic ecosystem have a strong temperature response. Here we identify sedges (Carex spp. and Eriophorum spp.) as key contributors to this high sensitivity using plant chamber experiments.
Wang H, Welch AM, Nagalingam S, Leong C, Czimczik CI, Tang J, Seco R, Rinnan R, Vettikkat L, Schobesberger S, Holst T, Brijesh S, Sheesley RJ, Barsanti KC, Guenther AB.   +14 more
europepmc   +2 more sources

Temperature sensitivity of the pyloric neuromuscular system and its modulation by dopamine [PDF]

, 2013
We report here the effects of temperature on the p1 neuromuscular system of the stomatogastric system of the lobster (Panulirus interruptus). Muscle force generation, in response to both the spontaneously rhythmic in vitro pyloric network neural activity
Kevin H. Hobbs, Burstein, Helaine J., Hooper, Scott L., Jeffrey B Thuma, Kevin H Hobbs, Seiter, Natasha S., Scott L. Hooper, Hobbs, Kevin H., Natasha S. Seiter, Scott L Hooper, Natasha S Seiter, Jeffrey B. Thuma, Helaine J. Burstein, Thuma, Jeffrey B., Helaine J Burstein   +14 more
core   +2 more sources