Results 81 to 90 of about 1,113,211 (316)

pH and Temperature Measurements in Biological Systems Utilizing the Environmental Sensitivity of Proton Transfer in Fluorophores [PDF]

, 2010
A great number of cellular processes can lead to local changes in proton concentration and temperature. So, it is desirable to be able to measure pH and temperature with non-invasive and spatially resolved methods.
Wong, Felix
core  

Temperature sensitivity of the pyloric neuromuscular system and its modulation by dopamine

, 2013
We report here the effects of temperature on the p1 neuromuscular system of the stomatogastric system of the lobster (Panulirus interruptus). Muscle force generation, in response to both the spontaneously rhythmic in vitro pyloric network neural activity
Kevin H. Hobbs, Burstein, Helaine J., Hooper, Scott L., Jeffrey B Thuma, Kevin H Hobbs, Seiter, Natasha S., Scott L. Hooper, Hobbs, Kevin H., Natasha S. Seiter, Scott L Hooper, Natasha S Seiter, Jeffrey B. Thuma, Helaine J. Burstein, Thuma, Jeffrey B., Helaine J Burstein   +14 more
core   +1 more source

Predation life history responses to increased temperature variability [PDF]

, 2014
This study was funded by a Postdoctoral fellowship to MB (SFRH/BPD/82259/2011) Fundacao para a Ciencia e Tecnologia (www.fct.pt/index.phtml.pt) and with a ‘‘Bolsista CAPES/BRASIL’’, (Project A058/2013) to AMVMS.The evolution of life history traits is ...
Barbosa, Miguel, Miguel Barbosa (633512), Pestana, Joao, Joao Pestana (633513), Miguel Barbosa, Amadeu M. V. M. Soares (324654), Soares, Amadeu M V M, Joao Pestana, Amadeu M. V. M. Soares, Soares, Amadeu M. V. M., Amadeu M V M Soares   +10 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Inscription and Thermal Stability of Fiber Bragg Gratings in Hydrogen-Loaded Optical Fibers Using a 266 nm Pulsed Laser

Photonics
Fiber Bragg gratings (FBGs) have gained substantial research interest due to their exceptional sensing capabilities. Traditionally, FBG fabrication has required the use of pre-hydrogenated fibers and high-cost laser systems such as excimer lasers at 193 ...
Xiangxi Zhu, Zixuan Xin, Haoming Zhu, Hongye Wang, Xin Cheng, Hwa-Yaw Tam, Hang Qu, Xuehao Hu   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Study on the changes in the temperature sensitivity of spring phenology of typical woody plants in the Qinling Mountains region

Frontiers in Earth Science
To reveal the responses of plant phenology and climate change in the Qinling Mountains region, the phenological data of seven woody plants in the Qinling Mountains region from 1964 to 2020 were selected to analyze the patterns and characteristics of ...
Shanhong Zhang, Qing Meng, Qian Ma, Hongying Bai, Shujuan Li   +4 more
doaj   +1 more source

Amplifying the Temperature Sensitivity of Zero-Field Splitting in Mn(II) Through Ligand Tuning

, 2023
Controlling the temperature response of magnetic resonance properties is an essential step toward novel molecular thermome-ters or quantum sensing platforms. To date, however, demonstrations of using molecular design to control the temperature dependence
Siyoung, Sung, Amanda, Gin, Indrani, Bhowmick, Cassidy, Jackson, Anthony, Campanella, Roxanna, Martinez, Joseph, Zadrozny, Andrew, Ozarowski   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source