Results 41 to 50 of about 322,385 (264)

An On‐Surface Reaction Confined within a Porous Molecular Template [PDF]

Chemistry – A European Journal, 2017
AbstractOn‐surface reactions based on metal‐catalysed Ullmann coupling have been successfully employed to synthesise a wide variety of covalently coupled structures. Substrate chemistry and topology are both known to effect the progression of an on‐surface reaction; offering routes to control efficiency and selectivity.
Chris J. Judd, Neil R. Champness, Alex Saywell   +2 more
openaire   +3 more sources

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Application of Surface Molecular Imprinting Technology in Sample Pretreatment for Food Analysis: A Review [PDF]

Shipin Kexue
In recent years, surface molecular imprinting technology has drawn a lot of attention for its application in sample pretreatment for food analysis. Due to the complexity of the food matrix, there are high requirements for the sensitivity and selectivity ...
SHI Xinyu, WANG Qing, ZHANG Yanqing
doaj   +1 more source

Impact of Mesoporous Silicon Template Pore Dimension and Surface Chemistry on Methylammonium Lead Trihalide Perovskite Photophysics

Advanced Materials Interfaces, 2020
In influencing fundamental properties—and ultimately device performance—of lead halide perovskites, interfacial interactions play a major role, notably with regard to carrier diffusion and recombination.
Viviana C.P. da Costa, Roberto Gonzalez‐Rodriguez, Kyle Frohna, Géraud Delport, Samuel D. Stranks, Leigh T. Canham, Jeffery L. Coffer   +6 more
doaj   +1 more source

Metal-organic framework template-guided electrochemical lithography on substrates for SERS sensing applications

Nature Communications, 2023
The templating method holds great promise for fabricating surface nanopatterns. To enhance the manufacturing capabilities of complex surface nanopatterns, it is important to explore new modes of the templates beyond their conventional masking and molding
Youyou Lu, Xuan Zhang, Liyan Zhao, Hong Liu, Mi Yan, Xiaochen Zhang, Kenji Mochizuki, Shikuan Yang   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Electric-driven flexible-roller nanoimprint lithography on the stress-sensitive warped wafer

International Journal of Extreme Manufacturing, 2023
Surface nanopatterning of semiconductor optoelectronic devices is a powerful way to improve their quality and performance. However, photoelectric devices’ inherent stress sensitivity and inevitable warpage pose a huge challenge on fabricating ...
Yu Fan, Chunhui Wang, Jiaxing Sun, Xiaogang Peng, Hongmiao Tian, Xiangming Li, Xiaoliang Chen, Xiaoming Chen, Jinyou Shao   +8 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source