Results 71 to 80 of about 765,179 (286)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
A template-free, ultra-adsorbing, high surface area carbonate nanostructure. [PDF]
PLoS ONE, 2013 We report the template-free, low-temperature synthesis of a stable, amorphous, and anhydrous magnesium carbonate nanostructure with pore sizes below 6 nm and a specific surface area of ∼ 800 m(2) g(-1), substantially surpassing the surface area of all ...
Johan Forsgren +4 more
doaj +1 more source
Endodontic management of pulp canal obliteration using a new single-tooth template: A case series
Indian Journal of Dental Research, 2021 Background: Guided Endodontics is suggested as a reliable method for management of teeth with pulp canal obliteration (PCO). The guide used for this usually involves multiple teeth to gain stability but is bulky.
Natanasabapathy Velmurugan +8 more
doaj +1 more source
Geometry-Aware Network for Non-Rigid Shape Prediction from a Single View [PDF]
, 2018 We propose a method for predicting the 3D shape of a deformable surface from a single view. By contrast with previous approaches, we do not need a pre-registered template of the surface, and our method is robust to the lack of texture and partial ...
Agudo, Antonio +5 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Comparison of Observed Galaxy Properties with Semianalytic Model Predictions using Machine Learning
, 2021 With current and upcoming experiments such as WFIRST, Euclid and LSST, we can observe up to billions of galaxies. While such surveys cannot obtain spectra for all observed galaxies, they produce galaxy magnitudes in color filters.
Chartab, Nima +3 more
core
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Surface adsorbed templates for directing the crystal growth of entacapone as monitored using process analytical techniques [PDF]
, 2013 Crystallization of entacapone (E-2-cyano-N,N-diethyl-3-(3,4-dihydroxy-5- nitrophenyl) propenamide) in acetone solution at the 500 mL scale using a self-assembled layer of the host material on Au(111) as a seeding template was studied and monitored using ...
Kwokal, A, Roberts, KJ, Čavužić, D
core +1 more source
Template-based surface reconstruction from cross-sections [PDF]
Computers & Graphics, 2016 In this work we explore a new approach to solving the problem of surface reconstruction from cross-section curves. Existing reconstruction methods focus on producing smooth interpolations and may require a large number of cross-sections to recreate feature-rich objects.
Michelle Holloway, Cindy Grimm, Tao Ju
openaire +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source