Results 111 to 120 of about 3,144,500 (368)

An FCM–GABPN Ensemble Approach for Material Feeding Prediction of Printed Circuit Board Template

open access: yesApplied Sciences, 2019
Accurate prediction of material feeding before production for a printed circuit board (PCB) template can reduce the comprehensive cost caused by surplus and supplemental feeding.
Shengping Lv   +4 more
doaj   +1 more source

The search for black hole binaries using a genetic algorithm

open access: yes, 2009
In this work we use genetic algorithm to search for the gravitational wave signal from the inspiralling massive Black Hole binaries in the simulated LISA data. We consider a single signal in the Gaussian instrumental noise.
Antoine Petiteau   +14 more
core   +1 more source

Road blocks on paleogenomes - polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA [PDF]

open access: yes, 2010
Although the last few years have seen great progress in DNA sequence retrieval from fossil specimens, some of the characteristics of ancient DNA remain poorly understood. This is particularly true for blocking lesions, i.e.
Briggs, A.   +5 more
core   +2 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Diverse Systems for Efficient Sequence Insertion and Replacement in Precise Plant Genome Editing

open access: yesBioDesign Research, 2020
CRISPR-mediated genome editing has been widely applied in plants to make uncomplicated genomic modifications including gene knockout and base changes.
Yingxiao Zhang, Yiping Qi
doaj   +1 more source

‘Genetic Coding’ Reconsidered : An Analysis of Actual Usage [PDF]

open access: yes, 2015
I thank George Pandarakalam for research assistance; Hans-Jörg Rheinberger for hosting my stay at the Max Planck Institute for History of Science, Berlin; and Sahotra Sarkar and referees of this journal for offering detailed comments.
Stegmann, Ulrich E.
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Ribosomal small subunit sequence diversity of Scutellospora within single spores and roots of bluebell from a woodland community. [PDF]

open access: yes, 1999
Roots of bluebell (Hyacinthoides nonscripta) were sampled from a woodland in Yorkshire,UK and spores of an arbuscular mycorrhizal fungus Scutellospora sp., were obtained from the surrounding soil.
Clapp, J.P., Fitter, A.H., Young, J.P.W.
core   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

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