Results 101 to 110 of about 121,448 (310)
A Mathematical Analysis of the Long-run Behavior of Genetic Algorithms for Social Modeling [PDF]
We present a mathematical analysis of the long-run behavior of genetic algorithms that are used for modeling social phenomena. The analysis relies on commonly used mathematical techniques in evolutionary game theory.
Waltman, L.R., Eck, N.J.P. van
core +1 more source
Arabidopsis thaliana Inspired Genetic Restoration Strategies [PDF]
, 2013 A controversial genetic restoration mechanism has been proposed for the model organism Arabidopsis thaliana. This theory proposes that genetic material from non-parental ancestors is used to restore genetic information that was inadvertently corrupted ...
Hatton, Donagh, O'Donoghue, Diarmuid
core
Bio-ProtocolGene-edited human pluripotent stem cells provide attractive model systems to functionally interrogate the role of specific genetic variants in relevant cell types.
Berta de La Cruz +6 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Population genetics of bottlenose dolphins (Tursiops truncatus) from an Anglo-Saxon archaeological site in comparison with modern populations. [PDF]
, 2004 Bottlenose dolphins {Tursiops truncatus) exhibit a cosmopolitan distribution, being found in temperate and tropical oceans throughout the world. Members of this species in the waters surrounding Britain are the most northerly populations and show a ...
Nichols, Courtney Dawn
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Functional mapping of a trypanosome centromere by chromosome fragmentation identifies a 16-kb GC-rich transcriptional "strand-switch" domain as a major feature. [PDF]
, 2005 Trypanosomatids are an ancient family that diverged from the main eukaryotic lineage early in evolution, which display several unique features of gene organization and expression.
Bromley, Elizabeth V +4 more
core +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Piecemeal Buildup of the Genetic Code, Ribosomes, and Genomes from Primordial tRNA Building Blocks
Life, 2016 The origin of biomolecular machinery likely centered around an ancient and central molecule capable of interacting with emergent macromolecular complexity. tRNA is the oldest and most central nucleic acid molecule of the cell.
Derek Caetano-Anollés +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Stem Cell ResearchThe X-linked Allan-Herndon-Dudley syndrome (AHDS) is a genetic disorder characterized by severe psychomotor impairment, resulting from mutations in the SLC16A2 gene, which encodes the thyroid hormone transporter MCT8 (monocarboxylate transporter 8 ...
Katarzyna A. Ludwik +5 more
doaj +1 more source