Results 81 to 90 of about 218,953 (302)

Template-dependent multiple displacement amplification for profiling human circulating RNA [PDF]

open access: yes, 2017
Multiple displacement amplification (MDA) is widely used in whole-genome/transcriptome amplification. However, template-independent amplification (TIA) in MDA is a commonly observed phenomenon, particularly when using high concentrations of random ...
Crosby, Seth D   +6 more
core   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Emerging trends in prime editing for precision genome editing

open access: yesExperimental and Molecular Medicine
Prime editing is an advanced genome editing technology that enables precise genetic modifications without inducing double-strand breaks or requiring donor DNA templates.
Jaesuk Lee, Jiyeon Kweon, Yongsub Kim
doaj   +1 more source

Self-Modeling Based Diagnosis of Software-Defined Networks

open access: yes, 2015
Networks built using SDN (Software-Defined Networks) and NFV (Network Functions Virtualization) approaches are expected to face several challenges such as scalability, robustness and resiliency.
Crespi, Noel   +2 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

An FCM–GABPN Ensemble Approach for Material Feeding Prediction of Printed Circuit Board Template

open access: yesApplied Sciences, 2019
Accurate prediction of material feeding before production for a printed circuit board (PCB) template can reduce the comprehensive cost caused by surplus and supplemental feeding.
Shengping Lv   +4 more
doaj   +1 more source

Neural network computation by in vitro transcriptional circuits [PDF]

open access: yes, 2004
The structural similarity of neural networks and genetic regulatory networks to digital circuits, and hence to each other, was noted from the very beginning of their study [1, 2]. In this work, we propose a simple biochemical system whose architecture
Hopfield, John J.   +2 more
core  

Isolation of a transcriptionally active element of high copy number retrotransposons in sweetpotato genome [PDF]

open access: yes, 2004
Many plant retrotransposons have been characterized, but only three families (Tnt1, Tto1 and Tos17) have been demonstrated to be transpositionally competent.
Aoki, Takahiro   +6 more
core   +1 more source

Eye tracking by genetic deformable template matching algorithm in video sequences [PDF]

open access: yesPort-Said Engineering Research Journal, 2013
Eye detection and tracking has broad applications in human-computer interaction, behavioural analysis, computer graphics, security, and biology systems. In this paper, we propose innovative eye detection and tracking method in video sequences. The proposed method incorporates deformable template matching and genetic algorithm to overcome problems ...
Randa Atta, Rehab Farouk, Sheren Zakaria
openaire   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

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