Results 111 to 120 of about 505,456 (287)

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini   +15 more
wiley   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

O tempo da escola e o tempo na escola como pauta na discussão de políticas de qualidade para a escola pública

open access: yesRevista Espaço Acadêmico, 2009
Eventualmente merece destaque no cenário educacional um tema recursivo: a qualificação da escola pública através de escolas em tempo integral.  Nesta perspectiva, o texto propõe a discussão do que se entende como tempo na escola e o tempo da escola, a ...
Rosimar Serena Siqueira Esquinsani
doaj  

Escola de Educação Integral em Tempo Integral à luz do Pensamento Complexo: análise dos conceitos relevantes da trajetória de implementação

open access: yesContexto & Educação, 2015
Resumo Esta proposta de pesquisa caracterizou como qualitativa de caso e teve como referencial teórico a Educação Integral e Pensamento Complexo numa análise dos conceitos relevantes da trajetória de implementação da Escola de Educação Integral em ...
nilton rodrigues menezes
doaj   +1 more source

Boston University Symphony Orchestra, February 3, 2000 [PDF]

open access: yes, 2000
This is the concert program of the Boston University Symphony Orchestra performance on Thursday, February 3, 2000 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue. Works performed were Symphony No. 4 in B-flat, Op.
School of Music, Boston University
core  

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

EVOLUTIONARY STABLE PROPERTIES OF POLITICAL PARTIES IN INDONESIA [PDF]

open access: yes, 2004
The major idea is to use memetics as an analytical tool on viewing how the existing political parties towards General Election 2004 creating formation of their presidential candidacy, ideology behind it, the change of political atmosphere it will bring ...
Khanafiah, Mr Deni   +2 more
core  

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou   +10 more
wiley   +1 more source

Acumulação - Tempo integral - Incompatibilidade horária

open access: yesRevista de Direito Administrativo, 1998
- Ilegalidade na acumulação de dois regimes de quarenta horas semanais pela incompatibilidade de cumprimento do regime de trabalho.
openaire   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

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