Results 111 to 120 of about 1,976,378 (263)

Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy

open access: yesAdvanced Science, EarlyView.
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan   +9 more
wiley   +1 more source

EDUCAÇÃO INTEGRAL E EDUCAÇÃO DE TEMPO INTEGRAL [PDF]

open access: yes, 2018
Este artigo tem por objetivo descrever diferenças e semelhanças entre a educação integral e de tempo integral, as primeiras iniciativas da implantação do tempo integral nas escolas de educação infantil e séries iniciais do ensino fundamental aqui no ...
Barbosa, Karina Martins
core  

Engineering Synergistic Intra‐/Intermolecular Conformational Locking via Side‐Chain Branching: A β‐Sheet‐Inspired Strategy for Planar NIR‐II Phototheranostic Aggregates

open access: yesAdvanced Science, EarlyView.
A bio‐inspired side‐chain branching strategy is developed to orchestrate a dual noncovalent conformational locking (NoCL) network, enabling the construction of perfectly planar NIR‐II phototheranostic aggregates. Such structural precision maximizes light‐harvesting efficiency and optimizes exciton dynamics, ensuring synchronized enhancements in NIR‐II ...
Cheng Lu   +11 more
wiley   +1 more source

Development and Applications of a Magnetism‐Aware General‐Purpose Atomic Cluster Expansion Potential for the Fe‐O‐H Ternary System

open access: yesAdvanced Science, EarlyView.
Hydrogen‐driven iron oxide reduction, water‐iron corrosion, and hydrogen embrittlement of metallic iron share the same Fe‐O‐H chemistry. A general‐purpose Atomic Cluster Expansion potential covers this chemistry across the full concentration range with explicit Ising‐like treatment of magnetism.
Baptiste Bienvenu   +5 more
wiley   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

open access: yesAdvanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon   +6 more
wiley   +1 more source

Programa Ensino Médio Inovador: atores e ações na construção de uma política pública. Estudo na Escola de Educação Básica Getúlio Vargas. [PDF]

open access: yes, 2016
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Curso de Ciências Sociais.Os jovens estão no centro de várias politicas públicas. Iniciativas voltadas para este público surgem como promessa do desmonte do
Machado, Talita Guímel Antunes
core  

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

open access: yesAdvanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan   +5 more
wiley   +1 more source

Posicionamento estratégico para uma escola em tempo integral

open access: yesPolítica e Gestão Educacional, 2017
Mediante a análise das tendências e exigências de mercado o colégio em estudo desenvolveu uma forma de ampliar a permanência do aluno na escola implantando o Projeto Escola em tempo Integral.
Romerito Valeriano da Silva   +4 more
doaj  

Trabalho

open access: yes, 2005
Tempo ...
Tempo Editorial
core  

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