Results 81 to 90 of about 1,742,108 (253)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Mining Spatio-temporal Data at Different Levels of Detail [PDF]

open access: yes, 2008
Presented at the 11th AGILE International Conference on Geographic Information Science (AGILE 2008), Girona, Spain, 5-8 May 2008In this paper we propose a methodology for mining very large spatio-temporal datasets.
Elena Camossi   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

TEMPORAL LANDSLIDE SUSCEPTIBILITY ASSESSMENT USING LANDSLIDE DENSITY TECHNIQUE [PDF]

open access: yesGeological Behavior, 2017
In this study, a temporal landslide assessment was carried out in a landslide prone areaalong the RanauTambunan road in Sabah, Malaysia. The assessment was based on landslides interpreted from 1978 and 1994 aerial photographs and also from fieldworks ...
NNorbert Simon,   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Agenda y Cuaderno de Nueva York: La paradoja entre la identidad í­ntima y la máscara múltiple

open access: yesOlivar: Revista de Literatura y Cultura Españolas, 2012
José Hierro es recordado en la historia de la literatura española por la poetización en sus obras de posguerra de un claro yo autoral, que cobra sentido casi siempre en cuanto englobado en el nosotros de una generación concreta y real: los textos ...
Elia Saneleuterio Temporal
doaj  

Riesgo de transmisión de la enfermedad de Chagas por intrusión de triatominos y mamíferos silvestres en Bucaramanga, Santander, Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introducción. La notificación de triatominos en las viviendas de algunos barrios de Bucaramanga motivó la realización de este estudio. Objetivo. Evaluar la intrusión de triatominos y mamíferos, así como algunos factores de riesgo para la enfermedad de ...
Marlene Reyes   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

TEORÍA Y PRÁCTICA DE LOPE Y MORATÍN: LA NUEVA COMEDIA, 'LA COMEDIA NUEVA'

open access: yes452ºF, 2014
En este artículo, por primera vez, se ponen en relación las teorías teatrales de dos dramaturgos españoles que crearon escuela: Lope de Vega y Leandro Fernández de Moratín.
Elia Saneleuterio Temporal
doaj  

Differential effects of top-down crossmodal attention on subjective timing of semantic and syntactic violations

open access: yesScientific Reports
Prior knowledge violations about the world’s consistency can distort subjective time perception. Scenes containing contextually irrelevant objects (i.e., semantic violations) are typically underestimated in duration (i.e., perceived shorter), whereas ...
Ourania Tachmatzidou   +2 more
doaj   +1 more source

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