Functional connectivity evidence of cortico-cortico inhibition in temporal lobe epilepsy. [PDF]
Epileptic seizures can initiate a neural circuit and lead to aberrant neural communication with brain areas outside the epileptogenic region. We focus on interictal activity in focal temporal lobe epilepsy and evaluate functional connectivity (FC ...
Doucet, Gaelle Eve +6 more
core +1 more source
Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy [PDF]
Giorgia Conte +9 more
openalex +1 more source
Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong +7 more
wiley +1 more source
Familial Mesial Temporal Lobe Epilepsy
Clinical, genetic, and MR characteristics of 68 patients with familial mesial temporal lobe epilepsy (MTLE) were analysed at the University of Campinas-UNICAMP, Brazil.
J Gordon Millichap
doaj +1 more source
Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy [PDF]
High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone.
Cmejla, Roman +5 more
core +3 more sources
Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong +7 more
wiley +1 more source
Temporal lobe epilepsy is a multifactorial neurological dysfunction syndrome that is refractory, resistant to antiepileptic drugs, and has a high recurrence rate.
Feng Chen +13 more
doaj +1 more source
Surgery for Temporal Lobe Epilepsy in Children [PDF]
This study aimed to assess the efficacy of magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT) in localizing epileptic foci in children with temporal lobe epilepsy (TLE).
Mohammad Faraji-rad +2 more
doaj +1 more source
A PIK3R2 Mutation in Familial Temporal Lobe Epilepsy as a Possible Pathogenic Variant
Temporal lobe epilepsy (TLE), the most common form of medically refractory focal epilepsy in adults, often requires surgery to alleviate seizures. By using next-generation sequencing, we identified a PIK3R2 mutation (NM_005027.4: c.265C > T; NP_005018.
Yishu Wang +8 more
doaj +1 more source
Observations on the relationship between verbal explicit and implicit memory and neuronal density in the left and right hippocampus in temporal lobectomy patients. [PDF]
The relationship between neuronal density and verbal memory in left and right hippocampal subfields was investigated in patients who underwent surgery for alleviation of temporal lobe epilepsy.
Beardsworth, Elizabeth +2 more
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