Results 51 to 60 of about 128,898 (315)

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Mesial temporal sclerosis presented with refractory seizure

APIK Journal of Internal Medicine, 2019
Background: Refractory complex partial seizures are common in temporal lobe epilepsy, which is often associated with sclerosis of the structures of the medial temporal lobes, particularly the hippocampus.
Malav Patel, Rishika Reddy, Sangram Biradar, V H Kumarswamy   +3 more
doaj   +1 more source

Resection of dominant fusiform gyrus is associated with decline of naming function when temporal lobe epilepsy manifests after the age of five: A voxel-based lesion-symptom mapping study

NeuroImage: Clinical, 2022
Summary: Objective: To determine patients’ characteristics and regions in the temporal lobe where resections lead to a decline in picture naming. Methods: 311 patients with left hemispheric dominance for language were included who underwent epilepsy ...
Caroline Reindl, Anna-Lena Allgäuer, Benedict A. Kleiser, Müjgan Dogan Onugoren, Johannes D. Lang, Tamara M. Welte, Jenny Stritzelberger, Klemens Winder, Michael Schwarz, Stephanie Gollwitzer, Regina Trollmann, Julie Rösch, Arnd Doerfler, Karl Rössler, Sebastian Brandner, Dominik Madžar, Frank Seifert, Stefan Rampp, Hajo M. Hamer, Katrin Walther   +19 more
doaj   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Hippocampal sclerosis – cause or consequence of mesial temporal lobe epilepsy in children? [PDF]

Romanian Journal of Neurology, 2012
Mesial temporal lobe epilepsy with hippocampal sclerosis is a well defined epileptic syndromic entity, especially in adults. In pediatric population, this syndrome has been less well studied, probable because of the particular electroclinical features of
Adriana Gabriela Albeanu, Sanda Magureanu, Dana Craiu, Lieven Lagae   +3 more
doaj   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Invasive nasal histiocytic sarcoma as a cause of epilepsy

Journal of Feline Medicine and Surgery Open Reports, 2018
Case summary A 10-year-old neutered female domestic shorthair cat was presented with an acute onset of neurological signs suggestive of a right-sided forebrain lesion, temporal lobe epilepsy and generalised seizure activity.
Koen M Santifort, Ben Jurgens, Guy CM Grinwis, Ingrid Gielen, Björn P Meij, Paul JJ Mandigers   +5 more
doaj   +1 more source

Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy [PDF]

, 2021
Giorgia Conte, Aida Menéndez‐Méndez, Sebastian Bauer, Hany El‐Naggar, Mariana Alves, Annette Nicke, Norman Delanty, Felix Rosenow, David C. Henshall, Tobías Engel   +9 more
openalex   +1 more source

Nomograms to predict naming decline after temporal lobe surgery in adults with epilepsy

Neurology, 2018
Objective To develop and externally validate models to predict the probability of postoperative naming decline in adults following temporal lobe epilepsy surgery using easily accessible preoperative clinical predictors.
R. Busch, Olivia Hogue, M. Kattan, M. Hamberger, D. Drane, B. Hermann, Michelle S Kim, Lisa Ferguson, W. Bingaman, J. González-Martínez, I. Najm, L. Jehi   +11 more
semanticscholar   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source