Results 81 to 90 of about 1,675,688 (289)

Temporal ¹⁰Be Variations in Ice [PDF]

Radiocarbon, 1983
10Be (T1/2 = 1.5·106y) is mainly produced in the atmosphere by cosmic ray spallation reactions on nitrogen and oxygen. About 70 % of the production takes place in the stratosphere. 10Be becomes attached to aerosols within a very short time. If 10Be is produced in the stratosphere some latitudinal mixing occurs.
Beer, Juerg, Andrée, Michael, Oeschger, Hans, Stauffer, Bernhard, Balzer, Richard, Bonani, Georges, Stoller, Christian, Suter, Martin, Wölfli, Willy, Finkel, Robert C.   +9 more
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Temporal and spatial variability in speakers with Parkinson's Disease and Friedreich's Ataxia [PDF]

, 2008
Speech variability in groups of speakers with Parkinson's disease (PD) and with Friedreich's ataxia was compared with healthy controls. Speakers repeated the same phrase 20 times at one of two rates (fast or habitual).
Anderson, Andrew, Howell, Peter, Lowit, Anja   +2 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Global trends in the incidence and mortality of esophageal cancer from 1990 to 2017

Cancer Medicine, 2020
Background The incidence and mortality of esophageal cancer are high, with 5.90 new cases and 5.48 deaths per 100 000 people worldwide in 2017. The prognosis of esophageal cancer is poor, with an overall 5‐year survival rate of less than 20%.
Jiahui Fan, Zhenqiu Liu, Xianhua Mao, Xin Tong, Tiejun Zhang, Chen Suo, Xingdong Chen   +6 more
doaj   +1 more source

Spatio-Temporal Variation of Heavy Metals in Cauvery River Basin [PDF]

, 2013
the present study water, sediment and soil samples of Cauvery basin was undertaken to evaluate the spatio-temporal variations in heavy metal concentrations between 2007 and 2009.
Prakash, K.L., Somashekar, R.K., Venkatesha Raju, K.   +2 more
core  

Variation of the Fine-Structure Constant and Laser Cooling of Atomic Dysprosium

, 2008
Radio-frequency electric-dipole transitions between nearly degenerate, opposite parity levels of atomic dysprosium (Dy) were monitored over an eight-month period to search for a variation in the fine-structure constant, $\alpha$.
Budker, D., Cingöz, A., Ferrell, S. J., Lamoreaux, S. K., Lapierre, A., Leefer, N. A., Nguyen, A. -T, Torgerson, J. R., Yashchuk, V. V.   +8 more
core   +3 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Relativistic effects in Ni II and the search for variation of the fine structure constant [PDF]

, 2000
Theories unifying gravity and other interactions suggest the possibility of spatial and temporal variation of physical ``constants'' in the Universe.
D. A. Varshalovich, J. D. Barrow, J. K. Webb, J. K. Webb, M. J. Drinkwater, M. T. Murphy, T. Damour, V. A. Dzuba, V. A. Dzuba, V. A. Dzuba, V. A. Dzuba, V. V. Flambaum, W. Marciano   +12 more
core   +4 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source