Results 111 to 120 of about 19,761,197 (221)

Immunohistochemical staining of Tenascin-C in esophageal squamous cell carcinoma cancer nest and stroma.

open access: yes, 2016
(A) Tenascin-C was weakly positive in basal layer epithelial cells and stromal fibroblasts of adjacent non-tumor esophageal mucosa. (B) Diffuse and strongly positive Tenascin-C expression was detected in stromal fibroblsts. (C) Strongly positive Tenascin-
Hak-Min Lee (843453)   +7 more
core   +1 more source

STUDY OF TENASCIN-C (TN-C) PROTEIN ROLE IN ORAL MALIGNANCY PROGRESSIVITY PROCESS BY MOLECULAR BIOLOGICAL APPROACH

open access: yesJournal of Dentistry Indonesia, 2006
The progressiveness of malignant tumors influenced by various complex factors. One of the important factors is Tenascin-C (Tn-C) protein, which can interact with fibrinectin as an anti adhesive or anti modulation protein.
Into Suhardjo   +1 more
doaj   +1 more source

Pyroptosis in Preeclampsia: Placenta‐to‐Maternal Organ Communication, Molecular Mechanisms, and Therapeutic Targets

open access: yesComprehensive Physiology, Volume 16, Issue 6, December 2026.
Schematic diagram illustrating the potential mechanisms and core molecules contributing to the development of PE via mediating pyroptosis: focus on trophoblasts and endothelial cells. Pyroptosis of trophoblast cells in the placenta of preeclampsia not only inhibits its invasion, migration, and differentiation, causing local infiltration and ...
Xianyi Zhou   +5 more
wiley   +1 more source

Changes in the expression of the extracellular matrix molecules tenascin-C and tenascin-R after 3-acetylpyridine-induced lesion of the olivocerebellar system of the adult rat.

open access: yes, 1997
In the central nervous system of rodents, the extracellular matrix glycoproteins tenascin-C and tenascin-R are expressed predominantly by astrocytes and oligodendrocytes respectively.
Schachner M   +3 more
core   +1 more source

Detection of tenascin-C in surgically excised choroidal neovascular membranes.

open access: yes, 2000
Increase of tenascin-C (TN-C) expression has been found in pathologic tissues in which angiogenesis occurs. The aim of this study was to investigate TN-C expression in human choroidal neovascularization (CNV)
Zardi L   +4 more
core   +1 more source

4‐Methylumbelliferone Restores Age‐Related Changes in Perineuronal Nets, Memory, and Neuroinflammation

open access: yesGlia, Volume 74, Issue 12, December 2026.
Brain aging alters perineuronal nets and neuroinflammation. 4‐methylumbelliferone reversed these aging‐associated changes. 4‐methylumbelliferone reduced age‐associated cognitive decline. Six months of chronic oral treatment was well tolerated. ABSTRACT Aging‐associated cognitive decline is closely linked to dysregulated glial activity and chronic ...
Anda Cimpean   +7 more
wiley   +1 more source

Further Insights Into the Mechanisms of Lymph Node Metastasis

open access: yesCancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Metastasis of malignant tumors arising from epithelial organs to sentinel lymph nodes has important implications for prognosis, staging, and therapeutic decision‐making. Recent insights into anatomic pathways, pathogenesis, molecular interactions, and genetic factors have encouraged scientists and clinicians to develop drugs that target ...
S. David Nathanson   +5 more
wiley   +1 more source

Integrated Multi‐Omics Analysis of Human Cerebrospinal Fluid in Traumatic Spinal Cord Injury: An Exploratory Pilot Study

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Integrated proteomic and metabolomic profiling of human cerebrospinal fluid outlines a distinct molecular landscape of acute traumatic spinal cord injury. This exploratory analysis highlights a novel GOT2‐associated metabolic signature, involving concurrent decreases of GOT2, methionine, and 4‐acetamidobutanoic acid.
Wenkang Jiang   +9 more
wiley   +1 more source

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

open access: yesClinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang   +8 more
wiley   +1 more source

Induction of tenascin-C by cyclic tensile strain versus growth factors: distinct contributions by Rho/ROCK and MAPK signaling pathways

open access: yes, 2004
Expression of the extracellular matrix (ECM) protein tenascin-C is induced in fibroblasts by growth factors as well as by tensile strain. Mechanical stress can act on gene regulation directly, or indirectly via the paracrine release of soluble factors by
Sarasa-Renedo, Ana   +5 more
core   +1 more source

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