Results 191 to 200 of about 19,761,197 (221)
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Analysis of structure and function of tenascin-C
The International Journal of Biochemistry & Cell Biology, 2006Tenascin-C is a multidomain large extracellular matrix glycoprotein composed of six monomers. The size of tenascin-C monomers (180-250 kDa) varies as a result of an alternative splicing of the fibronectin repeats at the pre-mRNA level. For the first time we applied bioinformatic and molecular modeling procedures, for detailed analysis of the ...
Jakub, Pas +6 more
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Tenascin-C in human cardiac pathology
Clinica Chimica Acta, 2012Tenascin-C (TN-C), a hexameric extracellular matrix glycoprotein, is a pleiotropic regulator of a variety of cell functions associated with embryogenesis, wound healing, cell proliferation, differentiation, motility, and nerve regeneration. Due to its role in remodeling processes, TN-C is involved with many pathologic states including cardiac and ...
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Ectopic expression of tenascin-C
Journal of Cell Science, 2003We read, with much interest, the recent Research Article by Jarvinen et al. ([Jarvinen et al., 2003][1]), in which the authors show that, after removing the cast from an immobilized rat hind leg, within 8 weeks tenascin-C (TN-C) expression is increased in tendon and the myotendinous junction ...
Matthias Chiquet, Martin Flück
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Cell Adhesion and Communication, 1996
Tenascin-C is an extracellular matrix glycoprotein with trophic and repulsive properties, involved in migratory processes in CNS. Previous reports demonstrated that this molecule is produced and secreted by astrocytes. Preliminary data on fibroblasts and astrocytes have suggested that bFGF may modulate tenascin-C expression.
M, Mahler +4 more
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Tenascin-C is an extracellular matrix glycoprotein with trophic and repulsive properties, involved in migratory processes in CNS. Previous reports demonstrated that this molecule is produced and secreted by astrocytes. Preliminary data on fibroblasts and astrocytes have suggested that bFGF may modulate tenascin-C expression.
M, Mahler +4 more
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Annals of Anatomy - Anatomischer Anzeiger, 2004
Different distributions of tenascin-C and -X are found in various organs. However, the role of the tenascin family in the process of formation in the papillae epithelium during development is poorly understood. In order to find more information an tenascin-C and -X distributions during tongue development, immunohistocheminical studies have been carried
Kazuhiro, Watanabe +2 more
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Different distributions of tenascin-C and -X are found in various organs. However, the role of the tenascin family in the process of formation in the papillae epithelium during development is poorly understood. In order to find more information an tenascin-C and -X distributions during tongue development, immunohistocheminical studies have been carried
Kazuhiro, Watanabe +2 more
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Tenascin-C and the development of articular cartilage
Matrix Biology, 1995In comparison to the vast literature on articular cartilage structure and function, relatively little is known about how articular cartilage forms during embryogenesis and is endowed with unique phenotypic properties, most notably the ability to persist and function throughout postnatal life.
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The roles of Tenascin C in kidney diseases
American Journal of Physiology-Cell PhysiologyTenascin C (TNC), an extracellular matrix glycoprotein, is crucial for embryonic development and tissue repair, inflammation, extracellular matrix remodeling, and fibrosis, particularly in kidney diseases. Although its expression is typically low in healthy adult kidneys, TNC is upregulated in various kidney disease conditions, including acute kidney ...
Tim Caspers +2 more
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How to detect and purify tenascin-C
2018The extracellular matrix molecule tenascin-C (TNC) was discovered over 30 years ago, and its tightly regulated pattern of expression since sparked keen interest in the scientific community. In adult tissues, TNC expression is restricted to specific niches and areas of active remodeling or high mechanical strain.
Giblin, Sean +5 more
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Tenascin-C, Tenascin-R and Tenascin-X: A Family of Talented Proteins in Search of Functions
Current Opinion in Cell Biology, 1993Harold P Erickson
exaly