Results 31 to 40 of about 19,761,198 (221)

Phylogenetic analysis of the tenascin gene family: evidence of origin early in the chordate lineage

open access: yesBMC Evolutionary Biology, 2006
Background Tenascins are a family of glycoproteins found primarily in the extracellular matrix of embryos where they help to regulate cell proliferation, adhesion and migration.
Tucker RP   +5 more
doaj   +1 more source

Serum tenascin-C predicts resistance to steroid combination therapy in high-risk Kawasaki disease: a multicenter prospective cohort study

open access: yesPediatric Rheumatology Online Journal, 2021
Background Tenascin-C (TN-C) is an extracellular matrix glycoprotein related to tissue inflammation. Our previous retrospective study conducted in 2016 revealed that the serum tenascin-C level was higher in patients with Kawasaki disease (KD) who were ...
Yukako Yoshikane   +10 more
doaj   +1 more source

Localization of tenascin in human skin wounds [PDF]

open access: yes, 1993
A total of 56 surgically treated human skin wounds with a wound age between 8h and 7 months were investigated. Tenascin was visualized by immunohistochemistry and appeared first in the wound area pericellularly around fibroblastic cells approximately 2 ...
Penning, R.   +4 more
core   +1 more source

Tenascins : prominent molecules in tumor stroma [PDF]

open access: yes, 2007
A very special connective tissue surrounds and interweaves solid tumors, the tumor stroma. Initially thought to only have a passive role, there is now more and more evidence accumulating that the tumor stroma plays an active function in the process of ...
Degen, Martin
core   +1 more source

Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs

open access: yesClinical and Translational Allergy, 2021
Background Tissue remodeling caused by increased MMPs is involved in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). We previously found higher levels of periostin and tenascin C in CRSwNPs, but whether they are associated with ...
Kun Du   +8 more
doaj   +1 more source

Tenascin C

open access: yes, 2022
Sepsis is a life-threatening condition, characterized by organ dysfunction and a dysregulated host response to infection. Despite having been a major cause of intensive care unit (ICU) mortality for decades, our understanding of its pathophysiology is still limited.
openaire   +3 more sources

Tenascin-C Signaling in melanoma

open access: yesCell Adhesion & Migration, 2014
Tenascin-C (TNC), a multifunctional matricellular glyco-protein, is highly expressed in the majority of melanoma cell lines and has been implicated in the progression of melanoma. A growing body of evidence has implicated the role of TNC in the process of invasion and metastasis for melanoma.
Hanshuang, Shao   +2 more
openaire   +2 more sources

Latent TGF-β Activation Is a Hallmark of the Tenascin Family

open access: yesFrontiers in Immunology, 2021
Transforming growth factor-β (TGF-β) isoforms are secreted as inactive complexes formed through non-covalent interactions between bioactive TGF-β entities and their N-terminal pro-domains called latency-associated peptides (LAP). Extracellular activation
Alexandre Aubert   +11 more
doaj   +1 more source

A model for prognosis of development of left ventricular systolic dysfunction in patients with acute myocardial infarction and type 2 diabetes mellitus taking into account tenascin C level

open access: yesZaporožskij Medicinskij Žurnal, 2016
The aim of the study was to elaborate a model for prediction of development of left ventricular systolic dysfunction in patients with acute myocardial infarction (AMI) and type 2 diabetes mellitus taking into account tenascin C level and estimation of ...
M. Yu. Koteliukh
doaj   +1 more source

Pleiotropic Role of Tenascin-C in Central Nervous System Diseases: From Basic to Clinical Applications

open access: yesFrontiers in Neurology, 2020
The extracellular matrix is composed of a variety of macromolecular substances secreted by cells, which form a complex network that supports and connects tissue structures, regulates the morphogenesis of tissues, and maintains the physiological ...
Chen Hanmin   +5 more
doaj   +1 more source

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