Results 1 to 10 of about 25,727 (257)

Biodegradable polymer nanocomposites for ligament/tendon tissue engineering

Journal of Nanobiotechnology, 2020
Ligaments and tendons are fibrous tissues with poor vascularity and limited regeneration capacity. Currently, a ligament/tendon injury often require a surgical procedure using auto- or allografts that present some limitations. These inadequacies combined
Magda Silva, Fernando N. Ferreira, Natália M. Alves, Maria C. Paiva   +3 more
doaj   +1 more source

Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells

Advanced Science, 2023
Stiffness is an important physical property of biomaterials that determines stem cell fate. Guiding stem cell differentiation via stiffness modulation has been considered in tissue engineering. However, the mechanism by which material stiffness regulates
Renwang Sheng, Jia Liu, Wei Zhang, Yifan Luo, Zhixuan Chen, Jiayu Chi, Qingyun Mo, Mingyue Wang, Yuzhi Sun, Chuanquan Liu, Yanan Zhang, Yue Zhu, Baian Kuang, Chunguang Yan, Haoyang Liu, Ludvig J. Backman, Jialin Chen   +16 more
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Historical evolution, hotspots, and trends in tendon tissue engineering: A bibliometric analysis

Regenerative Therapy
Introduction: As a significant branch of tissue engineering, tendon tissue engineering has developed rapidly, driven by advancements in new technologies and the refinement of medical theories. This study summarizes its development by analyzing historical
Wenlong Hou, Wenwen Liu, Mengtian Tan, Jiaxu Fang, Keye Cao, Xincheng Du, Haijun Zhang   +6 more
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Advances in the application of hydrogel-based scaffolds for tendon repair

Genes and Diseases
Tendon injuries often lead to joint dysfunction due to the limited self-regeneration capacity of tendons. Repairing tendons is a major challenge for surgeons and imposes a significant financial burden on society.
Renqiang Chen, Fanglin Chen, Kenian Chen, Jian Xu   +3 more
doaj   +1 more source

Mechanisms of tendon-bone interface healing: biomechanics, cell mechanics, and tissue engineering approaches

Journal of Orthopaedic Surgery and Research
The healing of tendon-bone contact surfaces involves complex biomechanical and biochemical interactions, with pivotal implications for sports medicine and rehabilitation.
Zhixiong Xu, Wensheng Xu, Tao Zhang, Long Luo   +3 more
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Harnessing the interplay between tendon stem/progenitor cell and microenvironment boosts tendon tissue regeneration

Engineered Regeneration
Tendon injuries are common musculoskeletal disorders characterized by limited natural healing capacity and inability to restore the original structure and function of tendons. Tendon tissue engineering based on tendon stem/progenitor cells (TSPCs) offers
Hong Zhang, Yujian Xu, Yangwu Chen, Kun Zhao, Tianshun Fang, Youguo Liao, Xiangming Ye, Xiao Chen, Zi Yin   +8 more
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Models of tendon development and injury

BMC Biomedical Engineering, 2019
Tendons link muscle to bone and transfer forces necessary for normal movement. Tendon injuries can be debilitating and their intrinsic healing potential is limited.
Sophia K. Theodossiou, Nathan R. Schiele
doaj   +1 more source

Reprogramming tendon healing: a guide to novel molecular tools

Frontiers in Bioengineering and Biotechnology
Tendons are a frequent site of injury, which greatly impairs the movement and locomotion of patients. Regrettably, injuries at the tendon frequently require surgical intervention, which leads to a long path to recovery.
Carlos Julio Peniche Silva, Elizabeth R. Balmayor, Martijn van Griensven   +2 more
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Macromolecular crowding in human tenocyte and skin fibroblast cultures: A comparative analysis

Materials Today Bio
Although human tenocytes and dermal fibroblasts have shown promise in tendon engineering, no tissue engineered medicine has been developed due to the prolonged ex vivo time required to develop an implantable device.
Adrian Djalali-Cuevas, Mandy Rettel, Frank Stein, Mikhail Savitski, Stephen Kearns, Jack Kelly, Manus Biggs, Ioannis Skoufos, Athina Tzora, Nikitas Prassinos, Nikolaos Diakakis, Dimitrios I. Zeugolis   +11 more
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Surgical repair of Achilles tendon rupture in dogs: a review of the literature, a case report and new perspectives

Veterinární Medicína, 2010
Achilles tendon rupture in the dog is a common traumatic lesion. An accurate evaluation of etiology, grade of the lesion with or without loss of tendon substance, and time elapsed from the trauma can guide the surgeon in choosing the best surgical ...
G. Spinella, R. Tamburro, G. Loprete, J.M. Vilar, S. Valentini   +4 more
doaj   +1 more source