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Flexor Tendon Tissue Engineering: Acellularized and Reseeded Tendon Constructs

Plastic and Reconstructive Surgery, 2009
Tissue engineering of flexor tendons requires scaffolds with adequate strength and biocompatibility. The biomechanical properties of acellularized and reseeded flexor tendon scaffolds are unknown. Acellularized tendons and reseeded constructs were tested to determine whether the treatment process had altered their biomechanical properties.Rabbit flexor
Alphonsus K S, Chong   +5 more
openaire   +2 more sources

Tissue Engineering Solutions for Tendon Repair

American Academy of Orthopaedic Surgeon, 2011
Tendon injuries range from acute traumatic ruptures and lacerations to chronic overuse injuries, such as tendinosis. Even with improved nonsurgical, surgical, and rehabilitation techniques, outcomes following tendon repair are inconsistent. Primary repair remains the standard of care.
Macalus V, Hogan   +5 more
openaire   +2 more sources

Decision support for tendon tissue engineering

Journal of Medical Engineering & Technology, 2006
The aim of this study is to provide decision support with artificial intelligence for tendon tissue engineering strategies. The experimental data of tissue-engineered tendons were integrated and standardized with a centralized database, and a decision support system was developed using both artificial neural networks and decision trees.
H, Ge, J, Xu, X, Zhou
openaire   +2 more sources

Tissue Engineering of Ligament and Tendon Healing

Clinical Orthopaedics and Related Research, 1999
Ligaments and tendons are bands of dense connective tissue that mediate normal joint movement and stability. Injury to these structures may result in significant joint dysfunction because they either heal by production of inferior matrix or do not heal at all.
S L, Woo   +5 more
openaire   +2 more sources

Tissue engineering of cartilage, tendon and bone

Frontiers of Medicine, 2011
Tissue engineering aims to produce a functional tissue replacement to repair defects. Tissue reconstruction is an essential step toward the clinical application of engineered tissues. Significant progress has recently been achieved in this field. In our laboratory, we focus on construction of cartilage, tendon and bone.
Hengyun, Sun   +5 more
openaire   +2 more sources

Repair of Tendon Defect with Dermal Fibroblast Engineered Tendon in a Porcine Model

Tissue Engineering, 2006
Harvesting autologous tenocytes for tendon engineering may cause secondary tendon defect at the donor site. Dermal fibroblasts are an easily accessible cell source and do not cause major donor site defect. This study aims to explore the possibility of tendon engineering using dermal fibroblasts.
Wei, Liu   +5 more
openaire   +2 more sources

In Vivo and In Vitro Tendon Engineering

Key Engineering Materials, 2007
Tendon is an important supportive tissue of human body responsible for normal physical activity. However, tendon damage and defect remain an important factor for causing disability. The rise of tissue engineering technology provides an effective means of tendon reconstruction and repair, which will bring promise for functional recovery.
Feng Xu   +5 more
openaire   +1 more source

Tendons: Engineering of Functional Tissues

2010
Modern advances in medical care have greatly improved survival rate and life expectancy following trauma or degenerative conditions, indirectly leading to an ever-increasing need for functional tissue substitutes to improve quality of life. As tendons have limited regeneration capacity, suitable substitutes are required for reconstruction.
D. I. Zeugolis, J. C. Y. Chan, A. Pandit
openaire   +1 more source

Tissue Engineering of Ligaments and Tendons

2013
Tissue engineering is a creative process where cells, scaffolds, and growth factors are combined to form a construct that can be used to replace or regenerate injured tissues. Cells that are specific to the tissue of interest can be used (for ligament, one might select the fibroblast) or can be earlier progenitor cells (e.g., mesenchymal stem cells ...
Patrick Vavken, Martha M. Murray
openaire   +1 more source

Tendons and Ligaments: Tissue Engineering

2016
Interest in biological technologies such as tissue engineering has dramatically increased, because it is now feasible to isolate living, healthy cells from tissues and organs, expand their number under cell culture conditions, combine the cells with biocompatible carrier materials in the form of scaffolds, and transplant them into patients.
Changming Guo, Myron Spector
openaire   +1 more source

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