Results 91 to 100 of about 6,328,469 (232)

Correction to: Three-Dimensional Cell Culture System for Tendon Tissue Engineering. [PDF]

Tissue Eng Regen Med, 2023
Son YH, Yang DH, Uricoli B, Park SJ, Jeong GJ, Chun HJ.   +5 more
europepmc   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

3D Printed Meter‐Scale Soft Origami Robots Capable of Load‐Bearing Actuation Via Crease Stiffness Modulation

Advanced Science, EarlyView.
Origami has inspired numerous soft deployable mechanisms for safe human‐robot interaction, while its intrinsic kinematic instability at arbitrary configurations limited their practical robotic application. This work presents a 3D printed meter‐scale origami robotic actuator capable of load‐bearing deformation through creaseline stiffness modulation.
Sung Yol Yu, Sang‐Joon Ahn, Wonchul Lee, Seunguk Moon, Hyun‐Jin Hong, Kyu‐Jin Cho   +5 more
wiley   +1 more source

Harnessing the interplay between tendon stem/progenitor cell and microenvironment boosts tendon tissue regeneration

Engineered Regeneration
Tendon injuries are common musculoskeletal disorders characterized by limited natural healing capacity and inability to restore the original structure and function of tendons. Tendon tissue engineering based on tendon stem/progenitor cells (TSPCs) offers
Hong Zhang, Yujian Xu, Yangwu Chen, Kun Zhao, Tianshun Fang, Youguo Liao, Xiangming Ye, Xiao Chen, Zi Yin   +8 more
doaj   +1 more source

Three-Dimensional Cell Culture System for Tendon Tissue Engineering. [PDF]

Tissue Eng Regen Med, 2023
Son YH, Yang DH, Uricoli B, Park SJ, Jeong GJ, Chun HJ.   +5 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Mesoporous Particle Embedded Nanofibrous Scaffolds Sustain Biological Factors for Tendon Tissue Engineering. [PDF]

ACS Mater Au, 2023
Rinoldi C, Kijeńska-Gawrońska E, Heljak M, Jaroszewicz J, Kamiński A, Khademhosseini A, Tamayol A, Swieszkowski W.   +7 more
europepmc   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Decellularized tilapia fish skin: A novel candidate for tendon tissue engineering. [PDF]

Mater Today Bio, 2022
Liu Z, Yu MZ, Peng H, Liu RT, Lim T, Zhang CQ, Zhu ZZ, Wei XJ.   +7 more
europepmc   +1 more source

Ethical issues in tissue engineering

, 2008
Tissue Engineering (or regenerative medicine) is a rapidly developing field of research pursued by very different branches of medicine. The most results are published by orthopedists [28] and cardiologists, but meanwhile, there is nearly no special ...
Welin, Stellan,
core   +1 more source