Results 111 to 120 of about 6,328,469 (232)

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

open access: yesAdvanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu   +12 more
wiley   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

open access: yesAdvanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu   +7 more
wiley   +1 more source

Role of tendon-derived stem cells in tendon and ligament repair: focus on tissue engineer

open access: yesFrontiers in Bioengineering and Biotechnology
This review offered a comprehensive analysis of tendon and ligament injuries, emphasizing the crucial role of tendon-derived stem cells (TDSCs) in tissue engineering as a potential solution for these challenging medical conditions.
Wei He   +8 more
doaj   +1 more source

An investigation into accelerated rehabilitation strategies following an achilles tendon rupture [PDF]

open access: yes
Background Rupture of the Achilles tendon occurs in over 11,000 people annually in the UK. Traditional management using cast immobilisation is being slowly replaced by immediate weight bearing rehabilitation, but currently there is no consensus ...
Kearney, Rebecca S.
core  

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

open access: yesAdvanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo   +5 more
wiley   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

open access: yesAdvanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan   +8 more
wiley   +1 more source

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen   +12 more
wiley   +1 more source

Ocular Tissue Engineering [PDF]

open access: yes, 2016
Tissue engineering emerged back in the 1990s as a new concept to overcome the problem of tissue and organ failure. Over recent decades, there has been incredible progress towards the regeneration of tissues such as bone, heart valves, cartilage, cornea ...

core   +1 more source

Hydroxyapatite-doped polycaprolactone nanofiber membrane improves tendon–bone interface healing for anterior cruciate ligament reconstruction

open access: yesInternational Journal of Nanomedicine, 2015
Fei Han,1,* Peng Zhang,2,* Yaying Sun,2 Chao Lin,1 Peng Zhao,1 Jiwu Chen2 1Shanghai East Hospital, The Institute for Biomedical Engineering and Nanoscience, Tongji University School of Medicine, Tongji University, 2Department of Sports Medicine, Huashan
Han F   +5 more
doaj  

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