Results 101 to 110 of about 6,328,469 (232)

Unravelling the Distinct Phenotype and Mechanosensitive Properties of Different Tendon Cell Populations

Advanced Science, EarlyView.
Tendon interfascicular and fascicular matrix cells are isolated and cultured, revealing distinct phenotypes and mechanosensitive responses. Interfascicular matrix cells exhibit marked stiffness‐dependent phenotypic plasticity, whereas fascicular matrix cells remain comparatively stable.
S. E. Grossemy, D. E. Zamboulis, N. S. Khatib, M. R. Fazal, C. C. Gains, A. Giannopoulos, T. Hopkins, C. Bevan, Y. Aggarwal, M. M. Knight, H. R. C. Screen   +10 more
wiley   +1 more source

The current status of various preclinical therapeutic approaches for tendon repair

Annals of Medicine
Tendons are fibroblastic structures that link muscle and bone. There are two kinds of tendon injuries, including acute and chronic. Each form of injury or deterioration can result in significant pain and loss of tendon function.
Wenqing Liang, Chao Zhou, Yongjun Deng, Lifeng Fu, Jiayi Zhao, Hengguo Long, Wenyi Ming, Jinxiang Shang, Bin Zeng   +8 more
doaj   +1 more source

Potential of Aligned Electrospun PLGA/SIS Blended Nanofibrous Membrane for Tendon Tissue Engineering. [PDF]

Polymers (Basel), 2023
Kim K, Kim H, Do S, Kim H.
europepmc   +1 more source

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

Advanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang, Ziqi Liu, Zhengqian Zhang, Yikun Cao, Junjun Ren, Peng Cheng, Jingjing Tian, Lingyun Xie, Xin Lu, Zhanwei Du, Yongzhuang Liu   +10 more
wiley   +1 more source

Electrospun Scaffolds Based on Poly(butyl cyanoacrylate) for Tendon Tissue Engineering. [PDF]

Int J Mol Sci, 2023
Bianchi E, Vigani B, Ruggeri M, Del Favero E, Ricci C, Grisoli P, Ferraretto A, Rossi S, Viseras C, Sandri G.   +9 more
europepmc   +1 more source

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

Advanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu, Renxian Wang, Dingding Wang, Quanzhong Ren, Ling Wang, Fangfang Duan, Guihe Yang, Ruixuan Yu, Yi Wang, Yingyu Zhang, Zetong Zang, Chuqi Li, Weijia Liu, Wenshuang Zhang, Yi Yuan, Zitong Cheng, Xiaoguang Cheng, Junbo Liang, Yajun Liu   +18 more
wiley   +1 more source

Artificial Single-Layer, Multi-Layer, and Gradient Scaffolds for Enhancing the Healing of Tendon-to-Bone Interfaces: A Mini-Review

Orthopedic Research and Reviews
Tianyi Song,1 Lin Guo,1 Changcheng Wang,2 Mingcheng Li3 1Second Department of Orthopedics, Affiliated Zhongshan Hospital, Dalian University, Dalian, Liaoning, 116001, People’s Republic of China; 2Department of Biomedical Engineering, School of Biomedical
Song T, Guo L, Wang C, Li M
doaj  

Current Advances in Three-Dimensional Tissue/Organ Printing

, 2018
Three-dimensional (3D) tissue/organ printing is a major aspect of recent innovation in the field of tissue engineering and regenerative medicine. 3D tissue/organ printing aims to create 3D living tissue/organ analogues, and have evolved along with ...
Jang, J, Park, JH, Cho, DW, Lee, JS
core   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Strengthening Constitutive Motifs in Isotropic Fibrous Hydrogel for Exceptional Damage Resistance

Advanced Science, EarlyView.
An orientation‐free strategy is reported for fabricating damage‐resistant hydrogels by strengthening constitutive motifs in isotropic fibrous (IF) networks. Through nonsolvent quenching followed by salting‐out, IF networks are generated and their multiscale constituents are subsequently reinforced, yielding dense and crystalline isotropic nanofiber ...
Bolin Wan, Xule Yang, Liju Xu, Dong Qiu
wiley   +1 more source